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Unit outline_

IMMU2911: Immunobiology (Advanced)

Semester 1, 2025 [Normal day] - Camperdown/Darlington, Sydney

Immunobiology is the study of defence mechanisms that protect living organisms against life-threatening infections. In this unit of study you will explore the essential features of the host immune responses and how it evolved from unicellular organisms to complex multi-cellular organisms. Studies in animal and microbial immunobiology are leading to breakthroughs in veterinary and clinical medicine, including combatting infectious diseases, maximising transplant success, treating allergies, autoimmune diseases and cancer, as well as development of new vaccines to prevent disease. Understanding the immunobiology of plants also enables us to protect crops from disease which enhances our food security. In this unit of study you will be provided with a detailed overview of immunobiology as a basic research science. We will explore in detail the nature of the immune cells and molecules that recognise danger and how the immune system of animals and plants respond at the cellular and molecular level. Advanced practical and tutorial sessions are designed to illustrate particular concepts introduced in other face-to-face activities. Further self-directed learning activities, including online learning activities, will facilitate integration of fundamental information and help you apply this knowledge to the ways in which the host organism defends against disease. This advanced version of Immunobiology has the same overall concepts as the mainstream unit but material is discussed in a manner that offers a greater level of challenge and academic rigour. Students enrolled in the advanced stream will participate in alternative components which may for example include guest lectures from experts. The nature of these components may vary from year to year.

Unit details and rules

Academic unit Department of Medical Sciences
Credit points 6
Prerequisites
? 
A WAM of 70 and a mark of 70 or above in [BIOL1XX7 or (BIOL1XX8 or BIOL1XX3 or MEDS1X01) or BIOL1XX2 or MBLG1XX1]
Corequisites
? 
None
Prohibitions
? 
IMMU2011
Assumed knowledge
? 

CHEM1XX1 or CHEM1903

Available to study abroad and exchange students

Yes

Teaching staff

Coordinator Scott Stimpson, scott.stimpson@sydney.edu.au
Lecturer(s) Carl Feng, carl.feng@sydney.edu.au
Mainthan Palendira, umaimainthan.palendira@sydney.edu.au
Scott Stimpson, scott.stimpson@sydney.edu.au
Kylie Shaddock, kylie.shaddock@sydney.edu.au
Tutor(s) Georges Grau, georges.grau@sydney.edu.au
The census date for this unit availability is 31 March 2025
Type Description Weight Due Length
Supervised exam
? 
Final exam
Final exams consists of multiple choice questions and SAQs
45% Formal exam period 2 hours
Outcomes assessed: LO1 LO2 LO3 LO4
Small continuous assessment Pre-practical quiz
MCQs about the content of the practical classes.
5% Multiple weeks 10 minutes
Outcomes assessed: LO5
Small continuous assessment AI Allowed Practical report
A series of questions to be answered and submitted based on the practical content.
5% Multiple weeks Questions related to practical work.
Outcomes assessed: LO4 LO5
Online task Early Feedback Task AI Allowed Early Feedback Task
The Early Feedback Task (EFT) designed to help you test your understanding of the first 3 weeks of lecture content and is of 0% weight towards your overall final grades, but is a tool to help identify if you are struggling early-on in this unit of study.
0% Week 03
Due date: 16 Mar 2025 at 23:59

Closing date: 16 Mar 2025
8 MCQs to be completed in 8 minutes.
Outcomes assessed: LO1 LO2
Assignment AI Allowed Journal Article Critque
A written critique of a journal article that will be provided to you in your tutorial class.
15% Week 09
Due date: 04 May 2025 at 23:59
2.5 - 4 pages
Outcomes assessed: LO1 LO2 LO4 LO5
Presentation group assignment AI Allowed Multimedia presentation
Oral presentation in tutorial classes.
15% Week 11 10 mins
Outcomes assessed: LO1 LO4 LO5
Tutorial quiz AI Allowed Theory of Practical Exam
MCQs and SAQs relating to the content of the practical classes.
15% Week 13
Due date: 29 May 2025 at 09:00
60 minutes
Outcomes assessed: LO1 LO2 LO3 LO4
group assignment = group assignment ?
AI allowed = AI allowed ?
early feedback task = early feedback task ?

Early feedback task

This unit includes an early feedback task, designed to give you feedback prior to the census date for this unit. Details are provided in the Canvas site and your result will be recorded in your Marks page. It is important that you actively engage with this task so that the University can support you to be successful in this unit.

Assessment summary

All assessments are outlined below and furhter details can be found on Canvas.

Assessment criteria

The University awards common result grades, set out in the Coursework Policy 2021 (Schedule 1).

As a general guide, a high distinction indicates work of an exceptional standard, a distinction a very high standard, a credit a good standard, and a pass an acceptable standard.

Result name

Mark range

Description

High distinction

85 - 100

To be awarded to students who, in their performance in assessment tasks,
demonstrate the learning outcomes for the unit at an exceptional standard
as defined by grade descriptors or exemplars established by the faculty
.

Distinction

75 - 84

To be awarded to students who, in their performance in assessment tasks,
demonstrate the learning outcomes for the unit at a very high standard as
defined by grade descriptors or exemplars established by the faculty.

Credit

65 - 74

To be awarded to students who, in their performance in assessment tasks,
demonstrate the learning outcomes for the unit at a good standard as
defined by grade descriptors or exemplars established by the faculty.

Pass

50 - 64

To be awarded to students who, in their performance in assessment tasks,
demonstrate the learning outcomes for the unit at an acceptable standard
as defined by grade descriptors or exemplars established by the faculty
.

Fail

0 - 49

To be awarded to students who, in their performance in assessment
tasks, fail to demonstrate the learning outcomes for the unit at an
acceptable standard established by the faculty. This grade, with
corresponding mark, should also be used in cases where a student fails
to achieve a mandated standard in a compulsory assessment, thereby
failing to demonstrate the learning outcomes to a satisfactory standard.
In such cases the student will receive the mark awarded by the faculty
up to a maximum of 49.

For more information see guide to grades.

Use of generative artificial intelligence (AI) and automated writing tools

Except for supervised exams or in-semester tests, you may use generative AI and automated writing tools in assessments unless expressly prohibited by your unit coordinator. 

For exams and in-semester tests, the use of AI and automated writing tools is not allowed unless expressly permitted in the assessment instructions. 

The icons in the assessment table above indicate whether AI is allowed – whether full AI, or only some AI (the latter is referred to as “AI restricted”). If no icon is shown, AI use is not permitted at all for the task. Refer to Canvas for full instructions on assessment tasks for this unit. 

Your final submission must be your own, original work. You must acknowledge any use of automated writing tools or generative AI, and any material generated that you include in your final submission must be properly referenced. You may be required to submit generative AI inputs and outputs that you used during your assessment process, or drafts of your original work. Inappropriate use of generative AI is considered a breach of the Academic Integrity Policy and penalties may apply. 

The Current Students website provides information on artificial intelligence in assessments. For help on how to correctly acknowledge the use of AI, please refer to the  AI in Education Canvas site

Late submission

In accordance with University policy, these penalties apply when written work is submitted after 11:59pm on the due date:

  • Deduction of 5% of the maximum mark for each calendar day after the due date.
  • After ten calendar days late, a mark of zero will be awarded.

This unit has an exception to the standard University policy or supplementary information has been provided by the unit coordinator. This information is displayed below:

Written work submitted electronically after 11.59 pm on the due date will be considered to have been submitted late. For every calendar day up to and including ten calendar days after the due date, a penalty of 5% of the maximum awardable marks will be applied to late work. The penalty will be calculated by first marking the work, and then subtracting 5% of the maximum awardable mark for each calendar day after the due date. For work submitted more than ten calendar days after the due date a mark of zero will be awarded.

Academic integrity

The Current Student website provides information on academic integrity and the resources available to all students. The University expects students and staff to act ethically and honestly and will treat all allegations of academic integrity breaches seriously.

We use similarity detection software to detect potential instances of plagiarism or other forms of academic integrity breach. If such matches indicate evidence of plagiarism or other forms of academic integrity breaches, your teacher is required to report your work for further investigation.

Simple extensions

If you encounter a problem submitting your work on time, you may be able to apply for an extension of five calendar days through a simple extension.  The application process will be different depending on the type of assessment and extensions cannot be granted for some assessment types like exams.

Special consideration

If exceptional circumstances mean you can’t complete an assessment, you need consideration for a longer period of time, or if you have essential commitments which impact your performance in an assessment, you may be eligible for special consideration or special arrangements.

Special consideration applications will not be affected by a simple extension application.

Using AI responsibly

Co-created with students, AI in Education includes lots of helpful examples of how students use generative AI tools to support their learning. It explains how generative AI works, the different tools available and how to use them responsibly and productively.

Support for students

The Support for Students Policy reflects the University’s commitment to supporting students in their academic journey and making the University safe for students. It is important that you read and understand this policy so that you are familiar with the range of support services available to you and understand how to engage with them.

The University uses email as its primary source of communication with students who need support under the Support for Students Policy. Make sure you check your University email regularly and respond to any communications received from the University.

Learning resources and detailed information about weekly assessment and learning activities can be accessed via Canvas. It is essential that you visit your unit of study Canvas site to ensure you are up to date with all of your tasks.

If you are having difficulties completing your studies, or are feeling unsure about your progress, we are here to help. You can access the support services offered by the University at any time:

Support and Services (including health and wellbeing services, financial support and learning support)
Course planning and administration
Meet with an Academic Adviser

WK Topic Learning activity Learning outcomes
Week 01 What is an immune system and why is it important? Lecture (1 hr) LO2
The components of the immune system Lecture (1 hr) LO2
Week 02 The Innate immune system Lecture (1 hr) LO2
Innate immune sensing Lecture (1 hr) LO1 LO2
Introduction to microscopy & immunohistology Practical (3 hr) LO1 LO2 LO5
Week 03 The Complement System Lecture (1 hr) LO1 LO2
MHC and antigen presentation Lecture (1 hr) LO1 LO2
Why do we need an immune system? Tutorial (2 hr) LO1 LO5
Week 04 B cells and antibodies Lecture (1 hr) LO1 LO2
T cells Lecture (1 hr) LO1 LO4
Fundamental immunology laboratory techniques Practical (3 hr) LO5
Week 05 Killer T Cells Lecture (1 hr) LO2 LO3 LO4
Helper T cells Lecture (1 hr) LO2 LO3
Understanding a scientific journal article Tutorial (2 hr) LO1 LO2 LO5
Week 06 Initiation of lymphocyte responses Lecture (1 hr) LO3 LO4
Immune memory Lecture (1 hr) LO2 LO3 LO4
Agglutination, an example of antigen-antibody Interaction Practical (3 hr) LO4 LO5
Week 07 Cytokines: Types and key functions Lecture (1 hr) LO3 LO4
Immune Cell Movement Lecture (1 hr) LO3 LO4
Immune effector molecules and their use in medicine Tutorial (2 hr) LO1 LO2 LO3 LO5
Week 08 Evolution of the Immune System Lecture (1 hr) LO3 LO4
Plant Immunology I Lecture (1 hr) LO2 LO3
Monoclonal antibodies in research and the clinic Practical (3 hr) LO4 LO5
Week 09 Plant Immunology II Lecture (1 hr) LO3
Week 10 Veterinary Immunology I Lecture (1 hr) LO1 LO2 LO3
Veterinary Immunology II Lecture (1 hr) LO1 LO2 LO3
Manipulating the immune system Tutorial (2 hr) LO5
Week 11 Immunology & disease: Autoimmunity and allergy Lecture (1 hr) LO1 LO3 LO4
Immunology & Disease: Transplantation Lecture (1 hr) LO1 LO3 LO4
Principles & practical applications of immunoassays Practical (3 hr) LO4 LO5
Week 12 Immunology & Disease: Host defense and vaccination Lecture (1 hr) LO1 LO3 LO4
Immunology & disease: Tumour Immunology Lecture (1 hr) LO1 LO2 LO3 LO4
Scientific communication Tutorial (2 hr) LO5

Attendance and class requirements

Attendance will be recorded from students' arrival date on campus or from February 25th, whichever is the earliest. From February 25th (week 1), students enrolled in this unit should engage with and study all online content, as directed in the Canvas site, including the submission of any required formative tasks and completion of any asynchronous activities.

It is expected that students attend at least 80% of the practicals and tutorials in this unit of study.

All students should make best efforts to attend all on campus classes they are timetables for, this includes live lectures, tutorials and practical classes. Attendance will be recorded for all classes.

Study commitment

Typically, there is a minimum expectation of 1.5-2 hours of student effort per week per credit point for units of study offered over a full semester. For a 6 credit point unit, this equates to roughly 120-150 hours of student effort in total.

Required readings

Abbas, Lichtman & Pillai Basic Immunology: Functions and Disorders of the Immune System 7th Ed. 2024.

Learning outcomes are what students know, understand and are able to do on completion of a unit of study. They are aligned with the University's graduate qualities and are assessed as part of the curriculum.

At the completion of this unit, you should be able to:

  • LO1. Differentiate the types of immunity
  • LO2. Compare and contrast the cells & molecules of immunity in more multiple organisms
  • LO3. Describe, using multiple examples, how plants and animals recognise and respond to pathogens
  • LO4. Demonstrate how principles of immunology can be used to tackle health problems
  • LO5. Master cutting edge immunology techniques, analyse & interpret the data generated from experiments and effectively communicate the results

Graduate qualities

The graduate qualities are the qualities and skills that all University of Sydney graduates must demonstrate on successful completion of an award course. As a future Sydney graduate, the set of qualities have been designed to equip you for the contemporary world.

GQ1 Depth of disciplinary expertise

Deep disciplinary expertise is the ability to integrate and rigorously apply knowledge, understanding and skills of a recognised discipline defined by scholarly activity, as well as familiarity with evolving practice of the discipline.

GQ2 Critical thinking and problem solving

Critical thinking and problem solving are the questioning of ideas, evidence and assumptions in order to propose and evaluate hypotheses or alternative arguments before formulating a conclusion or a solution to an identified problem.

GQ3 Oral and written communication

Effective communication, in both oral and written form, is the clear exchange of meaning in a manner that is appropriate to audience and context.

GQ4 Information and digital literacy

Information and digital literacy is the ability to locate, interpret, evaluate, manage, adapt, integrate, create and convey information using appropriate resources, tools and strategies.

GQ5 Inventiveness

Generating novel ideas and solutions.

GQ6 Cultural competence

Cultural Competence is the ability to actively, ethically, respectfully, and successfully engage across and between cultures. In the Australian context, this includes and celebrates Aboriginal and Torres Strait Islander cultures, knowledge systems, and a mature understanding of contemporary issues.

GQ7 Interdisciplinary effectiveness

Interdisciplinary effectiveness is the integration and synthesis of multiple viewpoints and practices, working effectively across disciplinary boundaries.

GQ8 Integrated professional, ethical, and personal identity

An integrated professional, ethical and personal identity is understanding the interaction between one’s personal and professional selves in an ethical context.

GQ9 Influence

Engaging others in a process, idea or vision.

Outcome map

Learning outcomes Graduate qualities
GQ1 GQ2 GQ3 GQ4 GQ5 GQ6 GQ7 GQ8 GQ9

This section outlines changes made to this unit following staff and student reviews.

The pre-practical quizzes time limit has been increased from 5 to 10 minutes per student feedback from previous years and will be opened and completed prior to practical classes.

Work, health and safety

You will be required to supply and wear your own lab coat and safety glasses for Practicals 2-5. We are unable to lend these items.

Disclaimer

The University reserves the right to amend units of study or no longer offer certain units, including where there are low enrolment numbers.

To help you understand common terms that we use at the University, we offer an online glossary.