Unit outline_

PHSI3010: Systems Physiology

Semester 1, 2026 [Normal day] - Camperdown/Darlington, Sydney

This unit of study will focus on the integration of key physiological processes important for basic body functions and for maintaining homeostasis. The approach to learning involves lectures, online activities, practicals and assessments designed to help you practice, solidify and integrate key concepts. As a final year Medical Science subject, assessments are designed for you to practice skills for entering postgraduate vocations including 1. Stakeholder engagement, 2. Research and 3. Clinical applications. The Unit is divided into three modules: 1. Muscle and Nerve: Explore a top down approach of the function and cellular makeup of the nervous system and muscle and their interaction in addition to nervous system control of organs in order to undertake activities of daily living. Practicals will have you apply your physiology knowledge to undertake assessments commonly used in a clinical settings in the field neuromuscular pathologies. 2. Cardiovascular Physiology: Explore important cellular and mechanical forces which play a role in physiological organ function. Lectures will provide insight into the links between tissue structure and function of the major mechanical systems, focusing on the cardiovascular system. Practicals will apply key principles in a wet lab setting and tutorials with practicing researchers will allow you to engage with leaders in the field. 3. Developmental Physiology: This module will provide an introduction to developmental physiology and biology, and regenerative medicine. The learning activities aim to equip you with a foundation of key concepts to understand classical approaches used in modern developmental biology and regenerative medicine and, begin building skills to enhance your critical thinking to interrogate diverse aspects of modern biology. Tutorials and practicals are designed to help you build these inquisitory skills and begin formulating scientific investigations to test your hypotheses.

Unit details and rules

Academic unit Department of Medical Sciences
Credit points 6
Prerequisites
? 
(PHSI2X05 and PHSI2X06) or (PHSI2X07 or MEDS2001) or [12 credit points from BCMB2X02 or BIOL2X29 or GEGE2X01 or MIMI2X02]
Corequisites
? 
None
Prohibitions
? 
PHSI3910
Assumed knowledge
? 

None

Available to study abroad and exchange students

Yes

Teaching staff

Coordinator Anna Waterhouse, anna.waterhouse@sydney.edu.au
Lecturer(s) Munira Xaymardan, munira.xaymardan@sydney.edu.au
Elizabeth Clarke, elizabeth.clarke@sydney.edu.au
Mathias Francois, mathias.francois@sydney.edu.au
The census date for this unit availability is 31 March 2026
Type Description Weight Due Length Use of AI
Written exam Final Exam
Final Exam: All Cardiovascular and Neuromuscular content.
40% Formal exam period 2 hours AI prohibited
Outcomes assessed: LO1 LO2 LO3 LO5
Experimental design Developmental Physiology Research Summary
Interpret existing data to design a research proposal and write a research summary.
10% Week 05
Due date: 27 Mar 2026 at 23:59

Closing date: 27 Mar 2026
750 words max, 500 words reference list AI allowed
Outcomes assessed: LO1 LO2 LO3 LO5
Written test In-semester test
In-semester test: All Developmental Physiology content.
20% Week 07
Due date: 13 Apr 2026 at 11:00
1 hour AI prohibited
Outcomes assessed: LO1 LO2 LO3 LO5
Presentation group assignment Novel Cardiovascular Therapeutics
Group oral presentation: Cardiovascular disease and treatments
15% Week 09
Due date: 28 Apr 2026 at 14:00

Closing date: 30 Apr 2026
Max 10 minutes AI allowed
Outcomes assessed: LO1 LO2 LO3 LO4 LO5
Written work Neuromuscular Clinical Case Report
Clinician education material on pathophysiology of a neuromuscular disease
15% Week 13
Due date: 25 May 2026 at 23:59

Closing date: 25 May 2026
750 words max, 500 words reference list AI allowed
Outcomes assessed: LO1 LO2 LO3 LO5
group assignment = group assignment ?

Assessment summary

The assessments in this unit are designed to help you receive feedback on your progress throughout the semester. You will be assessed on the modules in in-semester test and final exams, and from 1 assessment per module (3 total including 1 group assessment).

Assessment criteria

The University awards common result grades, set out in the Coursework Policy (Schedule 1).

As a general guide, a high distinction indicates work of an exceptional standard, a distinction a very high standard, a credit a good standard, and a pass an acceptable standard.

Result name

Mark range

Description

High distinction

85 - 100

Work of exceptional standard: Mastery of topics showing extensive integration and ability to transfer knowledge to novel contexts; treatment of tasks shows an advanced synthesis of ideas; demonstration of initiative, complex understanding and analysis; work is very well presented; all criteria addressed and learning outcomes achieved to an outstanding level.

Distinction

75 - 84

Work of superior standard: Excellent achievement, consistent evidence of deep understanding and application of knowledge in medical science; treatment of tasks shows advanced understanding of topics; demonstration of initiative, complex understanding and analysis; work is well-presented; all criteria addressed and learning outcomes achieved to a superior level.

Credit

65 - 74

Competent work demonstrating potential for higher study: Confident in explaining medical science processes, with evidence of solid understanding and achievement; occasional lapses indicative of unresolved issues; treatment of tasks shows a good understanding of topic; work is well-presented with a minimum of errors; all criteria addressed and learning outcomes achieved to a high level.

Pass

50 - 64

Work of acceptable standard: Satisfactory level of engagement with and understanding of topic; some inconsistencies in understanding and knowledge of medical science; work is adequately presented, with some errors or omissions, most criteria addressed and learning outcomes achieved to an adequate level.

Fail

0 - 49

Work not of acceptable standard: Unsatisfactory achievement and engagement with the discipline; inadequate understanding or fundamental misunderstanding of topics; most criteria and learning outcomes not clearly or adequately addressed or achieved; lack of effort/involvement in the unit.

For more information see guide to grades.

Use of generative artificial intelligence (AI)

You can use generative AI tools for open assessments. Restrictions on AI use apply to secure, supervised assessments used to confirm if students have met specific learning outcomes.

Refer to the assessment table above to see if AI is allowed, for assessments in this unit and check Canvas for full instructions on assessment tasks and AI use.

If you use AI, you must always acknowledge it. Misusing AI may lead to a breach of the Academic Integrity Policy.

Visit the Current Students website for more information on AI in assessments, including details on how to acknowledge its use.

Late submission

In accordance with University policy, these penalties apply when written work is submitted after 11:59pm on the due date:

  • Deduction of 5% of the maximum mark for each calendar day after the due date.
  • After ten calendar days late, a mark of zero will be awarded.

This unit has an exception to the standard University policy or supplementary information has been provided by the unit coordinator. This information is displayed below:

All assignments must be submitted by the due date and exams attended when they are scheduled. Students are expected to manage their time and to prioritise tasks to meet deadlines. Assessment items submitted after the due date without an approved extension using a special consideration or special arrangement form or request will incur penalties. Failure to meet assessment deadlines will incur mark deductions of 5% of the maximum awardable mark available for every day past the due date (for electronic submissions, days late includes Saturdays, Sundays and public holidays). These deductions will continue for 10 calendar days, until the solutions for the assignment are released, or marked assignments are returned to other students. At that point the mark awarded will be zero. For example, on an assignment given a mark of 70/100, the penalty would be 5 marks if submitted up to 24 hours late, resulting in a final mark of 65/100. If the assignment is submitted 6 days late, the penalty would be 30 marks and the final mark would be 40/100. If the assignment is more than 10 days late, submitted after the solutions for the assignment are released, or marked assignments are returned to other students, the final mark will be 0/100.

Academic integrity

The University expects students to act ethically and honestly and will treat all allegations of academic integrity breaches seriously.

Our website provides information on academic integrity and the resources available to all students. This includes advice on how to avoid common breaches of academic integrity. Ensure that you have completed the Academic Honesty Education Module (AHEM) which is mandatory for all commencing coursework students

Penalties for serious breaches can significantly impact your studies and your career after graduation. It is important that you speak with your unit coordinator if you need help with completing assessments.

Visit the Current Students website for more information on AI in assessments, including details on how to acknowledge its use.

Simple extensions

If you encounter a problem submitting your work on time, you may be able to apply for an extension of five calendar days through a simple extension.  The application process will be different depending on the type of assessment and extensions cannot be granted for some assessment types like exams.

Special consideration

If exceptional circumstances mean you can’t complete an assessment, you need consideration for a longer period of time, or if you have essential commitments which impact your performance in an assessment, you may be eligible for special consideration or special arrangements.

Special consideration applications will not be affected by a simple extension application.

Using AI responsibly

Co-created with students, AI in Education includes lots of helpful examples of how students use generative AI tools to support their learning. It explains how generative AI works, the different tools available and how to use them responsibly and productively.

Support for students

The Support for Students Policy reflects the University’s commitment to supporting students in their academic journey and making the University safe for students. It is important that you read and understand this policy so that you are familiar with the range of support services available to you and understand how to engage with them.

The University uses email as its primary source of communication with students who need support under the Support for Students Policy. Make sure you check your University email regularly and respond to any communications received from the University.

Learning resources and detailed information about weekly assessment and learning activities can be accessed via Canvas. It is essential that you visit your unit of study Canvas site to ensure you are up to date with all of your tasks.

If you are having difficulties completing your studies, or are feeling unsure about your progress, we are here to help. You can access the support services offered by the University at any time:

Support and Services (including health and wellbeing services, financial support and learning support)
Course planning and administration
Meet with an Academic Adviser

WK Topic Learning activity Learning outcomes
Week 01 Developmental Physiology: Unit/Module Overview, History/Development Introduction, Germ layers and organogenesis Lecture (3 hr) LO1 LO3
Week 02 Developmental Physiology: Heart development & abnormalities, Pharyngeal arches Lecture (3 hr) LO1 LO2 LO3
Week 03 Developmental Physiology: Cranial development, Bone development, Vasculogenesis and Angiogenesis Lecture (3 hr) LO1 LO5 LO2 LO3
Developmental Physiology: Tutorial Tutorial (3 hr) LO1 LO5 LO4 LO2 LO3
Week 04 Developmental Physiology: Lymphangiogenesis, Imaging vascular processes Lecture (3 hr) LO1 LO5 LO2 LO3
Developmental Physiology: Data interpretation for Research Summary Practical (3 hr) LO1 LO5 LO4 LO2 LO3
Week 05 Cardiovascular Physiology: Cell environments & structure/function, Heart structure/function, Heart/Vessel Contraction Lecture (3 hr) LO1 LO3
Week 06 Cardiovascular Physiology: Endothelial Cells, Smooth Muslce Cells, Tissue Specific Vasculature Lecture (3 hr) LO1 LO3
Cardiovascular Physiology: Myocardium Contraction (wet lab) Practical (3 hr) LO1 LO5 LO4 LO2 LO3
Week 07 Cardiovascular Physiology/Disease: Tutorial Tutorial (3 hr) LO1 LO5 LO4 LO2 LO3
Cardiovascular Physiology: Cardiovascular Diseases, Atherosclerosis Lecture (3 hr) LO1 LO2 LO3
Week 08 Cardiovascular Physiology: Thrombosis, Devices, Heart Failure Lecture (2 hr) LO1 LO2 LO3
Week 09 Muscle and Nerve: Motor Control and Motor Learning Lecture (2 hr) LO1 LO3
Cardiovascular Physiology/Disease: Presentation Tutorial (3 hr) LO1 LO5 LO4 LO2 LO3
Week 10 Muscle and Nerve: Locomotion, Postural Control, PD and Basal Ganglia Circuitry Lecture (2 hr) LO1 LO3
Muscle and Nerve: Clinical testing Practical (3 hr) LO1 LO5 LO4 LO2 LO3
Week 11 Muscle and Nerve: Motor Control and Motor Learning Tutorial (2 hr) LO1 LO3
Muscle and Nerve: ANS and Organ Control, Control of Digestion, Defecation and Urination Lecture (2 hr) LO1 LO3
Week 12 Muscle and Nerve: Diseases that affect the ANS, Revision Lecture (2 hr) LO1 LO2 LO3

Attendance and class requirements

Students are expected to attend a minimum of 80% of all Tutorial and Practical sessions to meet Learning Outcomes.

Study commitment

Typically, there is a minimum expectation of 1.5-2 hours of student effort per week per credit point for units of study offered over a full semester. For a 6 credit point unit, this equates to roughly 120-150 hours of student effort in total.

Required readings

Recommended reading will be listed on Canvas.

Learning outcomes are what students know, understand and are able to do on completion of a unit of study. They are aligned with the University's graduate qualities and are assessed as part of the curriculum.

At the completion of this unit, you should be able to:

  • LO1. Understand and communicate effectively key physiological principles relating to musculoskeletal/nervous system, the cardiovascular system and/or reproduction/development
  • LO2. Compare and contrast pathological data to data taken from a healthy population
  • LO3. Apply physiology knowledge to understand diseases of the musculoskeletal/nervous system, cardiovascular system and/or in reproduction/development
  • LO4. Collaborate with peers to understand and communicate with stakeholders (community, clinical populations and researchers) about physiological principles pertaining to the musculoskeletal/nervous system, cardiovascular physiology and/or reproduction/development.
  • LO5. Acquire and interpret research data and develop research communication skills in relation to systems physiology

Graduate qualities

The graduate qualities are the qualities and skills that all University of Sydney graduates must demonstrate on successful completion of an award course. As a future Sydney graduate, the set of qualities have been designed to equip you for the contemporary world.

GQ1 Depth of disciplinary expertise

Deep disciplinary expertise is the ability to integrate and rigorously apply knowledge, understanding and skills of a recognised discipline defined by scholarly activity, as well as familiarity with evolving practice of the discipline.

GQ2 Critical thinking and problem solving

Critical thinking and problem solving are the questioning of ideas, evidence and assumptions in order to propose and evaluate hypotheses or alternative arguments before formulating a conclusion or a solution to an identified problem.

GQ3 Oral and written communication

Effective communication, in both oral and written form, is the clear exchange of meaning in a manner that is appropriate to audience and context.

GQ4 Information and digital literacy

Information and digital literacy is the ability to locate, interpret, evaluate, manage, adapt, integrate, create and convey information using appropriate resources, tools and strategies.

GQ5 Inventiveness

Generating novel ideas and solutions.

GQ6 Cultural competence

Cultural Competence is the ability to actively, ethically, respectfully, and successfully engage across and between cultures. In the Australian context, this includes and celebrates Aboriginal and Torres Strait Islander cultures, knowledge systems, and a mature understanding of contemporary issues.

GQ7 Interdisciplinary effectiveness

Interdisciplinary effectiveness is the integration and synthesis of multiple viewpoints and practices, working effectively across disciplinary boundaries.

GQ8 Integrated professional, ethical, and personal identity

An integrated professional, ethical and personal identity is understanding the interaction between one’s personal and professional selves in an ethical context.

GQ9 Influence

Engaging others in a process, idea or vision.

Outcome map

Learning outcomes Graduate qualities
GQ1 GQ2 GQ3 GQ4 GQ5 GQ6 GQ7 GQ8 GQ9

This section outlines changes made to this unit following staff and student reviews.

Changes made to include more practice questions, skills development and feedback based on student feedback.

Work, health and safety

Students are required to comply with safety instructions in tutorial and practical sessions.

Disclaimer

Important: the University of Sydney regularly reviews units of study and reserves the right to change the units of study available annually. To stay up to date on available study options, including unit of study details and availability, refer to the relevant handbook.

To help you understand common terms that we use at the University, we offer an online glossary.