Skip to main content
Centres and institutes_

About the centre

A world-first centre tackling substance use and mental disorders
The Matilda Centre for Research in Mental Health and Substance Use is a multidisciplinary research centre committed to improving the health and wellbeing of people affected by co-occurring substance use and mental disorders.

Established in 2018, the Matilda Centre for Research in Mental Health and Substance Use aims to generate innovative and workable solutions to address substance use and mental disorders, which are currently the leading global causes of burden and disease in young people.

We work closely with research collaborators to share skills, synergise data and harness new technologies to develop and trial innovative prevention and early-intervention programs for co-occurring substance use and mental disorders.

We’re committed to

  • bringing together globally recognised researchers with a shared commitment to the prevention, early intervention and treatment of mental and substance use disorders
  • leading research to build the evidence base for a thriving and empowered younger generation
  • engaging with decision-makers and people with lived experience to enact real change
  • acting as a focal point and link between University of Sydney researchers, policy leaders and clinicians.

We facilitate collaboration

Our people are leading Australian and international researchers in addiction, mental health and youth health and our work builds dynamic, creative and global collaborations.

We invite those who share our mission to find workable solutions to prevent and treat comorbid mental health and substance use disorders to contact us.

We’re supervisors and mentors too

As leaders in our fields, we are proud to be educating a new generation of researchers, practitioners and teachers so that they too can think differently about substance use and mental health disorders.

We offer a range of opportunities for research students and early career researchers to study or work with us and receive mentorship from our internationally recognised researchers.

We can help you upskill

We also offer a range of training programs and resources for clinicians, school staff, families and the community to facilitate knowledge exchange around mental health and substance use, with the aim of improving support and changing lives.


Join us in our mission to help youth across the globe who are struggling with substance use or mental health by getting in touch.

Related articles

04 March 2021

QS rankings show global excellence for a broad range of subjects

Sports-related subjects were the standout in latest QS subject rankings result.
04 March 2021

How we tackle the obesity epidemic needs to change

On World Obesity Day our experts discuss policy change, research and treatment that aligns with this year's global theme "Every Body Needs Everybody."
03 March 2021

International experience for students continues during pandemic

Despite the COVID-19 border closures, University of Sydney students have still obtained international experience as part of their degree.
03 March 2021

Belly fat resistant to every-other-day fasting: study

Scientists have mapped out what happens to fat deposits during intermittent fasting (every second day), with an unexpected discovery that some types of fat are more resistant to weight loss in mice.
02 March 2021

Funding to support mental wellbeing of international students

Dr Isabella Choi from the University of Sydney is leading a project to provide better support for the mental wellbeing of Chinese international students through the use of an online program.
02 March 2021

Mardi Gras 2021: What we can learn from each other

With the 2021 Mardi Gras parade to be held on Saturday 6 March, we spoke with three current students about the most important lessons they have learned throughout their lived experiences, and the significance of Mardi Gras as an opportunity for growth as well as a celebration.
02 March 2021

Motive trumps incentive advertising in persuading consumers

Experts say advertising campaigns need to model positive internal motivation rather than external reasons like reward or punishment if they are to be effective.
01 March 2021

The best way to read Jane Austen? Out loud!

Ruth Wilson's PhD thesis proposes an unusual strategy in her re-imagining of established practices for teaching and reading the novels of Jane Austen. Read them aloud just as Jane Austen read them with family and friends.
01 March 2021

Wrasses dazzle: how fairy wrasses got their flamboyant colours

Sea level rises and falls during the Pliocene/Pleistocene epoch acted as a 'species pump', propelling fairy wrasses across oceans, and allowing them to evolve separately, into the 61 (and counting) species that exist today.
26 February 2021

Australian-first snapshot of healthcare-associated infections

A new Elsevier publication co-edited by academics in three states has started the process of bringing together information about healthcare-associated infections nationally, in line with international best practice.