New insights into disease and drug targets

From endogenous biological nanoscale vesicles to engineered nanoparticles

A collaboration between Professor Georges Grau, Professor Peter Lay and Professor Nicholas King.

This flagship project aims to discover new aspects of human diseases and new pathways for drug targeting from the myriad of endogenous biological nanovesicles (e.g. microparticles, exosomes, apoptotic bodies) released by the immune system in response to both infectious and non-infectious diseases.

To achieve this, we are developing powerful new nano-biospectroscopic protocols and advanced in-vitro spectroscopic modelling techniques to dynamically interrogate living cells and elucidate the beneficial and adverse effects of released endogenous nanovesicles.