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Examining the role of ABC transporter proteins in the development of Alzheimer’s disease

Cholesterol and other lipids have been shown to be related to the development of chronic disease including Alzheimer's disease. This project will study aspects of the cellular proce more...

Supervisor(s): Gelissen, Ingrid (Dr)

Display of Viral Surface Glycoprotein on Virus like particles (VPLS) for Structure and Immune Epitope Discovery

Unanchored recombinant soluble monomers are often the proteins used in many structure analyses and immunologic testing. But in reality viral surface glycoproteins are orientated, te more...

Supervisor(s): Lynch, Garry (Dr)

Control of complement cascade by labile disulphide bonds

The complement system is a key component of innate immunity that offers sophisticated protection against threats to the host organism. Complement is also an important component of t more...

Supervisor(s): Chiu, Joyce (Dr)

Molecular insights into a novel mammalian oxygen-sensing pathway

Oxygen (O2) is a vital biological resource most prominently known for its role as the final electron acceptor in aerobic respiration and, as such, adequate molecular mechanisms are more...

Supervisor(s): White, Mark (Dr), Mackay, Joel (Professor)

ASSESS THE GP GLYCOPROTEIN STRUCTURES OF EBOLA AND MARBURG VIRUS ENVELOPES, THEIR MUCIN-LIKE DOMAINS AND SITES FOR IMMUNE ATTACK

This project extends our published ebola (EBOV) gp's structures, and furthers our studies for immune targeting. Taking a holistic approach our studies aim to examine both the standa more...

Supervisor(s): Lynch, Garry (Dr)

STUDIES OF VARIABLE OR CONSERVED SURFACE PROTEIN SITES OF NEISSERIA MENINGITIDIS AS EPITOPES FOR STRAIN-SPECIFIC VACCINES OR BROAD-STRAIN (UNIVERSAL) VACCINES

The gram-negative Neisseria Meningititis (NM) remains a significant microbial problem and particularly lethal for the very young. Serogroup B strains are particularly troublesome an more...

Supervisor(s): Lynch, Garry (Dr)

Control of immune cell activity via a redox switch in integrin

Our immune system protects us from invasion of pathogens and toxic materials. Immune cells such as monocytes and neutrophils circulate in the blood to monitor foreign materials and more...

Supervisor(s): Chiu, Joyce (Dr)

Mechanisms of Transgenerational Epigenetic inheritance

We are interested in understanding the molecular mechanisms that allow a phenomenon called epigenetic inheritance to occur: that is, the transmission of non-genetic information from more...

Supervisor(s): Ashe, Alyson (Dr)

A Neurophotonic Platform as Universal Nerve Interface

We have assembled a team of experts whose combined expertise is essential to develop a universal nerve interface (UNI) by using neurophotonics technologies. more...

Supervisor(s): Palomba, Stefano (Associate Professor)

The influence of seminal plasma on sperm function and fertility

An opportunity is available for an outstanding PhD scholar in the area of reproductive biology. The project will investigate the factors in seminal plasma that influence male fertil more...

Supervisor(s): De Graaf, Simon (Associate Professor)