Circadian chip pilot study

Participants will first complete a series of questionnaires at the Brain & Mind Centre, and a pupillometry test (like a VR headset, testing exposure to light). Total time = 1 hour approximately You will be then given an actigraphy watch (like a fitbit) to wear for 10-14 days. Following confirmation of a normal sleep cycle from the actigraphy data, you will complete a 24 hour overnight sleep study within 2 weeks. You will arrive 12 hours before your regular bedtime to the Woolcock Institute Glebe, and have an IV cannula inserted, and skin temperature measurement buttons applied. Blood and saliva samples will be collected regularly throughout the 24 hours, and you will remain in a dimly lit room for the duration of your visit. You will not have access to electronic devices during this time (staff can operate a speaker with audiobooks, music, podcasts, etc.). You can bring paper materials for reading, writing, drawing, sketching, etc. Food and drinks will be provided. Following completion of the overnight sleep study, you will be given a $220 voucher for Coles.

You may be eligible to participate in this study if you:

Inclusion criteria:

• Aged 18-30
• No personal history or current mental or physical health conditions (as evidenced by screening questionnaires) or sleep disorder (by self-report)
• Regular sleep-wake pattern (determined by 10-14 days of actigraphy)
• English-speaking 

Exclusion criteria:

• Use of medications that affect sleep, melatonin, circadian rhythms, or alertness (e.g., melatonin, modafinil) 
• Evidence of other sleep, respiratory (e.g., sleep apnoea), neurological or primary medical conditions that could contribute to sleep-wake dysfunction 
• Significant alcohol or other substance misuse or substance dependence
• Regular shift work within 60-days prior to entry into the study. 
• Recent transmeridian travel across two or more time zones in the past one month (participants will be required to wait one month before entering the study)
• Open wounds or swelling around the eye
• Pregnancy or lactation
• Daily cigarette smoking

If you are interested in assisting with this important and exciting area of research, please contact the Youth, Mental Health & Technology team for further information via:

Email - ymh.research@sydney.edu

Text - 0422 588 787 (begin message with SLEEP)

Phone - 02 8036 5270