We turn pioneering research into real-world impact. Our diverse portfolio of innovations is ready for licensing, collaboration, and investment—spanning diagnostics, therapeutics, biomedical devices, optical technologies and more.
| Summary | A novel peptide-based technology disrupts immune complexes to prevent life-threatening blood clots caused by Heparin-induced thrombocytopenia (HIT), vaccine-induced thrombotic thrombocytopenia (VITT), and VITT-like diseases. All are severe immune reactions that cause catastrophic blood clots. |
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| Inventors | Freda Passam, Xuyu Liu, Jose Sail Perdomo |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | An antibody targeting Myc, with the potential to disrupt this otherwise "undruggable" target in various cancers. |
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| Inventors | Dr Mahdi Zeraati, Prof Marcel Dinger |
| Contact | karmen.kong@sydney.edu.au |
| Summary | A small device designed to mimic the appearance of hair, capable of interfacing with the brain for sensing, actuation, and as a delivery mechanism. |
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| Inventors | Omid Kavehei |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | A number of novel transcription factors associated with functional CAR-T cell phenotypes and proliferation, and methods of identifying more. |
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| Inventors | Salvatore Fiorenza, Cameron Turtle |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | This invention is a new copper-sensing molecular probe with applications for early diagnosis of Parkinson’s disease and management of amyotrophic lateral sclerosis. |
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| Inventors | Professor Elizabeth New, Professor Kay Double, Marcus Graziotto, Dr Liam Adair |
| Contact | julius.juarez@sydney.edu.au |
| Summary | This invention is an anti-venom treatment offering a broad-spectrum solution for neutralising toxins from various sources including snakes and marine life. |
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| Inventors | Professor Gregory Neely, Felicity Shu Yin Chung, Nicholas Casewell, Tian Du |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | This invention is a protein-based bioglue formulated to bind to neuronal tissues. |
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| Inventors | Dr Jingjing You, Jiawen Fan, Professor Matthew Simunovic, Professor Gerard Sutton, Dr Sheng Hua |
| Contact | julius.juarez@sydney.edu.au |
| Summary | A modified silica nanoparticle composition for bone regeneration. |
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| Inventors | Chun Xu, Chang Lei, Chengzhong Yu |
| Contact | karmen.kong@sydney.edu.au |
| Summary | Multispectral analysis of urinary biomarkers to non-invasively identify acute tubular necrosis, graft rejection, and non-rejection associated interstitial fibrosis and tubular atrophy. |
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| Inventors | Sonia Saad, Caroll Pollock, Ewa Goldys, Hon Lin Henry Wu, Yandong Lang |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | A series of new ligands that exhibit significantly higher affinity for a biomarker of neuroinflammation. |
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| Inventors | Dr Jonathan Danon, Professor Michael Kassiou, Greta Sohler, Dr Renee Sokias, Dr Tristan Reekie, Dr Eryn Werry |
| Contact | julius.juarez@sydney.edu.au |
| Summary | A novel software to increase CT image quality thereby improving accuracy and decreasing patient radiation dose. |
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| Inventors | Natasha Morton, Ricky Thomas O'Brien, Paul Keall, Jeffrey Barber, Jonathan Sykes, John Kipritidis |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | This invention relates to new phage-drug nanoconjugates for combating bacterial infections. |
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| Inventors | Professor Jonathan Iredell, Dr Hien Thi Duong, Huiping Huang |
| Contact | julius.juarez@sydney.edu.au |
| Summary | A novel software capable of predicting 3D lung motion with only 10 x-ray projections, for large scale lung disease screening. |
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| Inventors | Paul Keall, Hunor Kertesz, Owen Dillon, Hilary Byrne, Ricky O'Brien |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | A molecular diagnostic solution with over 95% specificity, leveraging DNA sequencing to objectively differentiate melanoma from benign naevi, thereby reducing the subjectivity and variability of traditional histopathology. |
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| Inventors | Richard A. Scolyer, Georgina Long, Ismael A. V. Correa, Andrew Colebatch, James Wilmott |
| Contact | taylor.syme@sydney.edu.au |
| Summary | A small molecule that reduces cholesterol accumulation in Neimann Pick Type C patient cells. |
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| Inventors | Associate Professor Thomas Grewal, Professor David Hibbs, Professor Paul Groundwater, Associate Professor Andrew Hoy, Dr Eric Sparkes, Dr Jonathan Du, Ms Mai K.L. Nguyen. |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | A novel phage extracellular vesicle (EV) conjugate designed to promote tissue repair in individuals with bacterial infections. |
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| Inventors | Professor Wojciech Chrzanowski, Dr Hien Thi Duong |
| Contact | julius.juarez@sydney.edu.au |
| Summary | This invention relates to peptide mimetic compounds, inspired by the natural healing capabilities of PDGF but engineered to circumvent the pitfalls of prolonged exposure that can lead to fibrosis. |
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| Inventors | A/Professor James Chong, Emily McKinna, Professor Richard James Payne, Daniel Ford, Richard Harvey, Dr Osvaldo Contreras |
| Contact | julius.juarez@sydney.edu.au |
| Summary | An instrumented spinal tool that uses intraoperative measurements and a reference database to guide optimal spinal cage sizing. |
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| Inventors | Ahmed Mounir Boudali, Elizabeth Clarke, Taha Shakoh, YH Yau, Bill Walter |
| Contact | karmen.kong@sydney.edu.au |
| Summary | A PSA-activated peptide sequence for prodrugs that enables targeted therapy for prostate cancer. A new approach for precision therapy for prostate cancer. |
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| Inventors | Trevor Hambley, Elisabeth Tondl |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | A novel software capable of tracking the movement of multiple targets during radiation therapy. |
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| Inventors | Emily Hewson, Paul Keall, Owen Thomas Dillon, Jeremy Booth |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary | A targeted TNBC (Triple Negative Breast Cancer) therapy with increased selectivity and efficacy and decreased toxicity. |
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| Inventors | Pegah Varamini, Sepideh Khazeni |
| Contact | julius.juarez@sydney.edu.au |
| Summary | Fibre sensors made of this low YM material will improve existing uses of OFS technology and open new opportunities in smart textiles, wearables, implantable therapeutic devices, healthcare, and soft robotics. |
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| Inventors | Professor Simon Fleming, Dr Richard Lwin, Dr Alessio Stefani, Dr Md Rejvi Kaysir |
| Contact | jeremy.cohen@sydney.edu.au |
| Summary | The innovation at hand is a nanoparticle bioconjugate that employs a dual-nanoparticle approach to target and bind to both cancer cells and immune cells. |
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| Inventors | A/Professor Veysel Kayser, Mariam Tarkistani |
| Contact | julius.juarez@sydney.edu.au |
| Summary | Novel inhibitors that target the two-partner secretion system, potentially blocking the secretion of virulence factors in Gram-negative bacteria, offering a new approach to combat bacterial infections. |
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| Inventors | Matthew Thomas Doyle, Alfred Hartojo, Peggy Cotter, Richard Johnson |
| Contact | karmen.kong@sydney.edu.au |
| Summary | A new gene editing technology that offers enhanced precision and the capability to insert large DNA sequences without off-target mutations or triggering error-prone DNA repair. |
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| Inventors | Sandro F Ataide, Rezwan Siddiquee, Ruth Hall |
| Contact | karmen.kong@sydney.edu.au |
| Summary | This invention presents a new method for assembling protein cages outside of cells, without the need for disassembly. The technology offers greater reliability, flexibility, and consistency compared to existing methods, as well as simplifying manufacturing processes, making it well-suited for applications in therapeutics, vaccines and more. |
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| Inventors | A/Prof Yu Heng Lau, Dr Taylor Szyszka and PhD candidate Rezwan Siddiquee |
| Contact | jeremy.cohen@sydney.edu.au |
| Summary | This technology chemically modifies polyhydroxyalkanoates by bonding them with polyamines to enhance their thermal, mechanical, and processing properties for advanced biomedical applications. Project details (PDF, 103KB) |
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| Inventors | Dr Sepehr Talebian, Chen Wang, Prof. Fariba Dehghani, A/Prof Sina Naficy |
| Contact | lulu.xue@sydney.edu.au |
| Summary | A novel Linear Maximum a Posteriori (LMAP) decoding method and decoder architecture for rate 1/2 convolutional codes that significantly reduces decoding complexity and delay while matching optimal MAP decoding performance. Project details (PDF, 99KB) |
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| Inventors | Prof Yonghui Li, Chentao Yue, Prof. Branka Vucetic |
| Contact | lulu.xue@sydney.edu.au |
| Summary | Innovative organic semiconductor nanoparticles designed to mimic human retinal photoreceptors for advanced retinal prosthetic applications. Project details (PDF, 99KB) |
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| Inventors | A/Professor Matthew Griffith, A/Professor Rebecca Lim |
| Contact | lulu.xue@sydney.edu.au |
| Summary | A technology that adds low cost and simple architecture to the existing advantages of photonics-based radar. |
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| Inventors | Dr Yang Liu, Mr Ziqian Zhang, Professor Benjamin Eggleton |
| Contact | jeremy.cohen@sydney.edu.au |
| Summary | An innovative method and system utilizing microbial enzyme-mediated hydrolysis combined with pre-treatment and post-treatment processes to efficiently recycle fibre-reinforced polymers into high-quality carbon and glass fibres. Project details (PDF, 99KB) |
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| Inventors | Dr Ali Hadigheh, Yaning Wei |
| Contact | lulu.xue@sydney.edu.au |
| Summary | An on-chip real-time versatile sensing system that can be applied to many in-situ and off-line measurement scenarios including electric vehicle battery monitoring, blood tests, and nanoparticles sensing. |
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| Inventors | Professor Xiaoke Yi, Dr Xiaoyi Tian |
| Contact | lulu.xue@sydney.edu.au |
| Summary | Fibre sensors made of this low YM material will improve existing uses of OFS technology and open new opportunities in smart textiles, wearables, implantable therapeutic devices, healthcare, and soft robotics. |
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| Inventors | Professor Simon Fleming, Dr Richard Lwin, Dr Alessio Stefani, Dr Md Rejvi Kaysir |
| Contact | jeremy.cohen@sydney.edu.au |
| Summary | An improved protein coating process that enables covalent attachment of any protein to a glass surface without using chemical linkers or any additional reagents, which could drive growth in the global medical coatings market. |
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| Inventors | Professor Marcela Bilek, Dr Clara Thao Hoang Tran, Dr Stuart Tallis Fraser, Dr Badwi Bob Boumelhem, Dr Aaron Gilmour |
| Contact | lulu.xue@sydney.edu.au |
| Summary | A revolutionary technology to help those grappling with complex communication needs. |
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| Inventors | Professor Alistair McEwan, Professor Petra Karlsson, Haifeng Zha |
| Contact | lulu.xue@sydney.edu.au |
| Summary | A compact wearable ECG monitoring device employing AI-based deep learning algorithms for accurate, real-time diagnosis of cardiac arrhythmia. |
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| Inventors | Professor Branka Vucetic, Associate Professor Zihuai Lin, Xucun Yan |
| Contact | lulu.xue@sydney.edu.au |
| Summary | A framework designed to support emergency nurses in assessing and managing emergency department patients after triage. |
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| Inventors | Belinda Kennedy, Julie Considine, Kate Curtis, John Mackenzie, Margaret Murphy, Sarah Kourouche, Margaret Fry, Ramon Shaban |
| Contact | karmen.kong@sydney.edu.au |
| Summary | An adaptation of the original HIRAID framework for residential aged care. |
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| Inventors | Professor Ramon Shaban, Dr Catherine Viengkham, Professor Kate Curtis AO, Professor Julie Considine AO (Deakin University), Professor Margaret Fry AM (UTS) |
| Contact | karmen.kong@sydney.edu.au |
| Summary | A custom-designed web-based platform for automating the administration of the Indigenous Tutorial Assistance Scheme-Tertiary Tuition (ITAS-TT). |
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| Creators | Designed at the University of Sydney by the Office of the DVC (Indigenous Strategy and Services) and developed by TechLab in Information and Communication Technology (ICT) |
| Contact | karmen.kong@sydney.edu.au |
| Summary | An online program that provides peer support tools, mental health literacy content and help seeking guidance for teenagers. |
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| Creators | Dr Louise White, Sophia Spallek, Ms An Nguyen, Ms Ainsley Furneaux‑Bate. |
| Contact | emma-louise.hunsley@sydney.edu.au |
| Summary |
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| Creators | Lee Wallace, Victoria Elizabeth Rawlings, Premeet Kaur Sidhu, Xavier Ho, Logan Timmins |
| Contact | karmen.kong@sydney.edu.au |
Commercialisation team
Our Commercialisation team is here to help you navigate licensing, collaboration and investment opportunities, so you can bring innovation to life.