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CHARACTERISATION OF ERUSIOLIN - A NEW PEPTIDE HORMONE

In this project we aim to characterise the function of a new gut-derived peptide we have discovered in human plasma, named erusiolin, which we hypothesise plays a role in appetite r more...

Supervisor(s): Larance, Mark (Dr)

UNDERSTANDING GENETIC VARIATIONS IN BONE

Functional genomics is a field that is undergoing major changes in practice due to the accessibility of gene editing technologies. Our team has developed methods for gene editing in more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Munns, Craig (Associate Professor)

GENE THERAPY FOR GENETIC BONE DISEASES

Gene therapy is becoming a practical approach to treat severe genetic conditions and in recent years conditions such as Spinal Muscular Atrophy (SMA) have been success stories. Our more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Munns, Craig (Associate Professor)

Structure-based drug design with Kynurenine Aminotransferase-2

Human kynurenine amino transferase-2 (KAT-2) forms the basis of a structure-based drug design study with implications for schizophrenia and gender differences.  The various asp more...

Supervisor(s): Church, W Bret (Dr)

Developing new antibiotics by targeting specific molecular interactions in bacteria

This project focuses on developing a new class of antibiotics by targeting specific molecular interactions in bacteria using a multi-disciplinary fragment-based drug design approach more...

Supervisor(s): Kwan, Ann (Dr)

Using metabolomics and other omics to guide new cancer therapies

This project will investigate cellular status and signaling in novel cancer therapies, especially new irradiation schemes in radiotherapy using metabolomics, transcriptomics and pro more...

Supervisor(s): Kwan, Ann (Dr), McKenzie, David (Professor)

Clinical and community applications of placebo and nocebo effects

Over the last two decades, a wealth of experimental studies has helped us to uncover the psychological mechanisms of placebo and nocebo effects. But a critical remaining question is more...

Supervisor(s): Colagiuri, Ben (Associate Professor)

Uncovering the source of CO2 that’s respired when dry soil is rewet

Soil respiration is one of the largest components of the global C cycle, but also one of the hardest to model. A key aspect of this difficulty is that we do not have a good mechanis more...

Supervisor(s): Warren, Charles (Associate Professor)

Do co-occurring plants avoid competing for N?

All plants require nitrogen, so how can species co-exist if they're competing for the same limiting resource? This project will examine the hypothesis that plants avoid competing fo more...

Supervisor(s): Warren, Charles (Associate Professor)

Plasma surface modification for applications in microfluidic diagnostic systems and implantable cardiovascular devices

You will develop novel hemocompatible, bioactive surfaces in microfluidic models for cardiovascular applications. The project is part of an existing collaboration between medic more...

Supervisor(s): Bilek, Marcela (Professor)