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Utility of Cerebrospinal fluid proteomics to define molecular mechanisms in brain disease of childhood.

Brain diseases of childhood are very common and result in significant disability, and cost to the nation. Common diseases include epilepsy, cerebral palsy, autism and mental health more...

Supervisor(s): Dale, Russell (Professor)

Facilitating treatments for neurodegenerative Parkinson’s disease

Opportunities exist to join a leading group conducting research into Parkinson's disease. Our group combines the disciplines of biochemistry, immunology, molecular biology and cell more...

Supervisor(s): Dzamko, Nicolas (Dr)

Neural Correlates of Chronic Cardiovascular Disease

Chronic cardiovascular disease (diabetes, obesity, heart disease) has a wide systemic physiological impact, including microstructural damage to the brain. Our group has an opportuni more...

Supervisor(s): Grieve, Stuart (Professor)

Brain Structural Connectomics and Tractographic Performance in Ultra-High Resolution Diffusion Imaging

Sydney Translational Imaging Laboratory (STIL) have an opportunity for a PhD student to investigate the structure of the brain's white matter fibres at a previously unseen level of more...

Supervisor(s): Grieve, Stuart (Professor)

Pharmacological targeting of sphingosine 1-phosphate receptors to promote remyelination in Alzheimer’s disease and multiple sclerosis

In this project you will investigate a new molecular pathway that is required for normal myelin formation, and the therapeutic potential of targeting this pathway to promote remyeli more...

Supervisor(s): Don, Anthony (Associate Professor)

Discovery and validation of new ceramide synthase inhibitors to treat metabolic disease

Ceramide synthase enzyme isoforms 1, 5, and 6, are heavily implicated as drivers of obesity, insulin resistance, and diabetes. Targeting these enzymes is expected to yield new thera more...

Supervisor(s): Don, Anthony (Associate Professor), Qi, Jacob (Dr)

Maternal autoimmunity increases risk of neurodevelopmental problems in offspring.

Maternal autoimmunity is a recognised risk factor for autism and other neurodevelopmental and psychiatric disorders in the offspring. It is well established in humans and animal mod more...

Supervisor(s): Dale, Russell (Professor), Hofer, Markus (Dr)

Impact of chronic inflammation on bowel and sexual function

Inflammatory bowel diseases (IBD) is difficult to treat and secondary pathological outcome can include decreased fertility. Also, many of the available treatments cause unwanted se more...

Supervisor(s): Witting, Paul (Dr)

Medical Image Analysis with Machine Learning Techniques

Develop artificial intelligence for computer-assisted diagnosis from medical scans. more...

Supervisor(s): Zhou, Luping (Dr)

Inferring the dimensionality of dynamical systems automatically using machine learning

This research will develop methods to infer the dimensionality of a dynamical system automatically, by adapting dimensionality reduction methods to high-dimensional time-series feat more...

Supervisor(s): Fulcher, Ben (Dr)