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Preventing rejection of transplanted organs without using immunosuppressive drugs

The project aims to identify molecular pathways to prevent rejection of transplanted organs in animal models and to apply these findings to clinical transplantation. more...

Supervisor(s): Bishop, Alex (Dr)

Regulatory T cells

Regulatory T cells (Tregs) control autoimmune, allergic and inflammatory responses, and are involved in organ transplantation and immune responses to cancer. more...

Supervisor(s): Fazekas, Barbara (Professor)

Interactions between porcine ligands and the human lymphocyte activating receptor NKG2D

Role of NKG2D in the human cellular immune response against porcine xenotransplants. more...

Supervisor(s): Sharland, Alexandra (Dr)

Interplay between Innate and adaptive immunity in kidney ischemia reperfusion injury and allograft rejection

This study is to investigate the link between innate and adaptive immunity in kidney ischemia reperfusion injury and allograft rejection with a view to identifying new therapeutic t more...

Supervisor(s): Chadban, Steve (Professor), Wu, Huiling (Associate Professor)

Unravelling mechanisms determining the balance between tolerance and immunity in the liver

Role of primary T cell activation in the liver in CD8 T cell tolerance more...

Supervisor(s): Bertolino, Patrick (Dr)

Bioethics, public health ethics, clinical ethics and the philosophy of medicine

Associate Professor Kerridge’s research focuses on the philosophical, moral and socio-cultural concepts, frameworks and issues that underpin health, health policy and biomedic more...

Supervisor(s): Kerridge, Ian (Professor)

The role of miRNAs in diabetic renal interstitial fibrosis

The central aim of the project is to define the therapeutic benefit of targeting miRNAs in renal interstitial fibrosis in diabetic nephropathy. more...

Supervisor(s): Pollock, Carol (Professor), Chen, Xin-Ming (Dr)

Tubular autophagy in diabetic nephropathy

The central aim of the project is to define the role of autophagy dysfunction leading to renal tubulointerstitial fibrosis in diabetic nephropathy. more...

Supervisor(s): Pollock, Carol (Professor), Chen, Xin-Ming (Dr)

Dendritic cells and control of T cell immune responses

DCs are unique antigen-presenting cells that can initiate (prime) CD4 T cell responses, as well as controlling the progression and subsequent reduction of the immune response, devel more...

Supervisor(s): Fazekas, Barbara (Professor)

Bioethics

Are you interested in the interaction between advances in biotechnology and society, or the complex relationship between morality, mental health and the law? Do you want to explore more...

Supervisor(s): Kerridge, Ian (Professor), Jordens, Christopher (Associate Professor), Mooney-Somers, Julie (Dr), Newson, Ainsley (Associate Professor)