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HUMAN MINIBRAINS GROWN FROM STEM CELLS

This project will involve CRISPR genome editing strategies combined with human stem cell derived mini-brains to investigate new neuronal factors that control development, cognitive more...

Supervisor(s): Neely, Greg (Professor)

Novel therapies for preventing kidney failure in chronic kidney disease

PhD and Master of Phil opportunities, at Centre for Transplantation and Renal Research, Westmead Institute for Medical Research, Westmead Clinical School, Faculty of Medicine and He more...

Supervisor(s): Zheng, Guoping (Dr), Harris, David (Professor)

Chemotherapy-induced neuropathic pain, fatigue, and cognitive impairments

Cancer and cancer treatments are associated with a wide range of side effects, including those of the nervous system. These present as neuropathic pain, fatigue, and cognitive impai more...

Supervisor(s): Johnston, Ian (Dr)

The role of key driver genes in the pathogenesis of acute renal allograft rejection

This is a PhD project. The successful applicant will be top up scholarship. This study will lead to publish high quality of papers and apply a new NHMRC project grant. more...

Supervisor(s): O'Connell, Philip (Professor), Hu, Min (Dr)

Novel therapy to prevent and treat kidney fibrosis

Progressive kidney disease is a global health burden most commonly caused by diabetes and obesity, which are dramatically on the rise. In Australia, 1 in 3 adults are at risk of dev more...

Supervisor(s): Saad, Sonia (Dr), Pollock, Carol (Professor)

Heart Failure, Oxygen and HIF

This project will investigate the physiological and metabolic changes seen in the heart in models of obstructive sleep apnoea. more...

Supervisor(s): Cook, Kristina (Dr), Farnham, Melissa (Dr)

Monocyte re-programming with increased cardiovascular disease risk

Cardiovascular disease (CVD) is the leading cause of death in Australia and an increasing number of people live with the condition. The main underlying cause is atherosclerosis, the more...

Supervisor(s): Medbury, Heather (Dr)

Pregnancy and Maternal Oral Health

Background: Recently, a number of studies have shown that poor oral health may impact on general health. Periodontal diseases have been identified as an independent risk factor for more...

Supervisor(s): Nanan, Ralph (Professor)

The global analysis of liver protein complexes during the response to intermittent fasting

In animals, short periods of nutrient deprivation, such as intermittent fasting, have been shown to provide benefits with regard to cancer risk/treatment and ageing. Our aims are to more...

Supervisor(s): Larance, Mark (Dr)

Generation of a sheep model of Batten disease using the CRISPR/Cas9 genome editing system

The neuronal ceroid lipofuscinoses (NCLs, Batten disease) are a group of fatal neurodegenerative inherited diseases in humans and animals (http://bdsra.org/). There is no cure, but more...

Supervisor(s): Tammen, Imke (Associate Professor), Grupen, Christopher Gerald (Associate Professor)