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Development of novel anti-cancer metastasis agents derived from omega-3 fatty acid metabolites

At present we have no therapies that prevent cancer spread. In this project we will develop novel w-3 fatty acid epoxide analogues that inhibit tumour metastasis. These derivatives more...

Supervisor(s): Murray, Michael (Professor)

Mitochondial DNA damage, potential target to reduce the development of renal disorders induced by maternal smoking .

Smoking rates are disproportionately high in disadvantaged populations, particularly in emerging economies, and increasing in women of child bearing age. more...

Supervisor(s): Saad, Sonia (Dr)

Expanding the scope of the Stetter reaction

Opportunities exist to build complex organic molecules using the organocatalytic Stetter reaction. more...

Supervisor(s): McErlean, Christopher (Associate Professor)

Combined, Correlative and Integrated Microscopy: Unraveling Biomolecular Structure-Function Activities in Cancer & Transendothelial Transport

Our team seek to understand the spatial and temporal mechanisms involved in the onset and progress of colorectal cancer by using state-of-the-art multidimensional microscopy and 3-D more...

Supervisor(s): Braet, Filip (Associate Professor)

Laboratory Exobiology: Prebiotic Environments in Ionic Liquids?

Life in the universe is widely presumed only to be viable in the ‘Goldilocks zone’ around a star, where liquid water is available.  Some have speculated that Titan more...

Supervisor(s): Warr, Gregory (Professor)

Gadolinium complexes as new theranostic agents for brain cancer

The 5-year survival rate for patients afflicted with aggressive and intractable brain tumours (gliomas) is less than 4%.  In this project, we will incorporate Gd3+ ions into mi more...

Supervisor(s): Rendina, Louis (Professor)

Carboranes as unique boron frameworks in medicinal chemistry

Boron-based drugs are increasingly being investigated in many disease categories, with numerous pharmaceutical companies (e.g. GSK, Anacor, and Takeda) dramatically expanding their more...

Supervisor(s): Rendina, Louis (Professor)

‘Magic Bullet’ Cancer Drugs and Antibiotics

We are building new kinds of cancer drugs and antibiotics: molecules that change their behaviour in the presence of their biological target, being chemically activated only when the more...

Supervisor(s): Rutledge, Peter (Professor)

Fluorescent sensors for oxidative stress

Oxidative stress is associated with all diseases of ageing, and there is therefore a need for better tools to identify and quantify the condition. We are developing novel fluorescen more...

Supervisor(s): New, Elizabeth (Associate Professor)

Positive computing applications - human-computer interaction to change the world

Develop software applications that help people live healthier, happier, empowering lives. more...

Supervisor(s): Calvo, Rafael A. (Associate Professor)