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Molecular insights into a novel mammalian oxygen-sensing pathway

Oxygen (O2) is a vital biological resource most prominently known for its role as the final electron acceptor in aerobic respiration and, as such, adequate molecular mechanisms are more...

Supervisor(s): White, Mark (Dr), Mackay, Joel (Professor)

Transformersomes: shape-shifting polymer nanostructures

Synthetic polymers can self-assemble into an impressive spectrum of well-defined nanoscale architectures that behave in intriguing ways, from catalysing chemical reactions to intera more...

Supervisor(s): Roberts, Derrick (Dr)

THE PATHOGENIC AND PROTECTIVE EFFECTS OF MICROGLIA IN CEREBRAL CYTOKINOPATHIES

Microglia are the primary immune cells of the brain and have the potential to both protect and contribute to neurological disease. Explore the molecular mechanisms that microglia us more...

Supervisor(s): Hofer, Markus (Dr)

Atmospheric water capture through passive cooling

The development of a theoretical model of atmospheric water capture, opening up the possibility of a new reliable source of water. more...

Supervisor(s): Alexander , Tristram (Dr), Neto, Chiara (Professor)

Defining the clinical and immunogenetic profile in antibody-associated demyelination

Masters or PhD opportunity ideally suited for a medical or neurology trainee or fellow with a commitment to building expertise in clinical and translational neuroimmunology. more...

Supervisor(s): Ramanathan, Sudarshini (Dr), Brilot-Turville, Fabienne (Dr), Dale, Russell (Professor)

Pain Phenotype Characterisation in Preclinical Models of Osteoarthritis

Osteoarthritis (OA) is the most common chronic joint disease, affecting 15% of the population and causing a significant socioeconomic burden. It is a debilitating condition characte more...

Supervisor(s): Zaki, Sanaa (Dr)

Responsive Metal-Organic Framework Materials

Metal-organic frameworks (MOFs) are a major new family of material that are attracting enormous interest due to their designable structures and advanced capabilities.  This pro more...

Supervisor(s): Kepert, Cameron (Professor)

TARGETING THE BRAIN VASCULATURE AS A TREATMENT FOR CEREBRAL TYPE I INTERFERONOPATHIES

Abnormal blood vessels are feature of cerebral type I interferonopathies. Discover how the endothelial cells that line the brain’s blood vessels contribute to disease in patie more...

Supervisor(s): Hofer, Markus (Dr)

HOW DIFFERENT CELL TYPES OF THE BRAIN CONTRIBUTE TO CEREBRAL CYTOKINOPATHIES

The brain consists of a large number of different cell types, including neurons, astrocytes, oligodendrocytes, microglia and endothelial cells. Discover how these different cell typ more...

Supervisor(s): Hofer, Markus (Dr)

Understanding the utility and yield of Next generation sequencing gene panels for the diagnosis of genetic movement disorders in children

Movement disorders are common in children, and include tics, dystonia, chorea, myoclonus and tremor. Other than tics, these disorders often have a genetic basis, which is ‘mon more...

Supervisor(s): Mohammad, Shekeeb (Dr)