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Examining the role of ABC transporter proteins in the development of Alzheimer’s disease

Cholesterol and other lipids have been shown to be related to the development of chronic disease including Alzheimer's disease. This project will study aspects of the cellular proce more...

Supervisor(s): Gelissen, Ingrid (Dr)

Fighting the spread of misinformation

The development of a quantitative measure of the spread of misinformation, for the purposes of developing a strategy to counter science denial. more...

Supervisor(s): Alexander , Tristram (Dr), Fulcher, Ben (Dr), Sharma, Manjula (Professor)

Conserved Regulatory Genes in Neurodevelopment

The present project aims to utilize the promising combination of 3D organoid technology and CRISPR genome editing, which will allow us to examine the roles of several conserved gene more...

Supervisor(s): Neely, Greg (Professor)

Atmospheric water capture through passive cooling

The development of a theoretical model of atmospheric water capture, opening up the possibility of a new reliable source of water. more...

Supervisor(s): Alexander , Tristram (Dr), Neto, Chiara (Professor)

The nutritional geometry of non-alcoholic fatty liver disease, cardio-metabolic health and lifespan

The global epidemic of obesity and type 2 diabetes (T2D) has been linked to increased consumption of ‘western diets’ containing an abundance of processed foods rich in s more...

Supervisor(s): Simpson, Stephen (Professor), Wali, Jibran (Dr)

Chemical synthesis and phenotypic validation of precision proteolysis targeted chimeras (PROTACs) for cancer and cardiovascular disease

Emerging from the interface between chemistry and biology, chemical biology has led to the establishment of several game-changing drug discovery paradigms. Among these revolutionary more...

Supervisor(s): Liu, Xuyu (Dr), Payne, Richard (Professor)

Data-driven modelling of social systems

The tools of physics will be applied to social dynamics data, to develop a predictive model, and ultimately inform policy decisions in the chosen area. more...

Supervisor(s): Alexander , Tristram (Dr)

Reconstruct trans-regulatory networks using multi-omics profiling and data integration

A major initiative in our group is to integrate trans-omics datasets generated by a state‐of‐the‐art mass spectrometer (MS) and next-generation sequencer (NGS) from various ce more...

Supervisor(s): Yang, Pengyi (Dr)

HOW DIFFERENT CELL TYPES OF THE BRAIN CONTRIBUTE TO CEREBRAL CYTOKINOPATHIES

The brain consists of a large number of different cell types, including neurons, astrocytes, oligodendrocytes, microglia and endothelial cells. Discover how these different cell typ more...

Supervisor(s): Hofer, Markus (Dr)

THE PATHOGENIC AND PROTECTIVE EFFECTS OF MICROGLIA IN CEREBRAL CYTOKINOPATHIES

Microglia are the primary immune cells of the brain and have the potential to both protect and contribute to neurological disease. Explore the molecular mechanisms that microglia us more...

Supervisor(s): Hofer, Markus (Dr)