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Geometric analysis of transcendental solutions of nonlinear systems

Modern science derives its power from mathematics. The project aims to capture, identify and describe pivotal, transcendental solutions of nonlinear systems that are universal in sc more...

Supervisor(s): Joshi, Nalini (Professor), Radnovic, Milena (Dr)

Develop single-cell mechanobiological methods for discovering molecular mechanisms of cardiovascular and neuronal mechanical force sensing

We are developing cutting-edge technologies for the following biomedical application: 1) define the mechanosensing functions of key protein players in the cardiovascular system such more...

Supervisor(s): Ju, Lining (Arnold) (Dr)

Ecological flows and floodplain trees, how do we estimate impacts?

Floodplain ecology provides important ecosystem functions, such a storage of flood peaks and filtration of sediments from water, as well as providing habitat for a range of native f more...

Supervisor(s): Vervoort, Willem (Associate Professor)

Molecular insights into a novel mammalian oxygen-sensing pathway

Oxygen (O2) is a vital biological resource most prominently known for its role as the final electron acceptor in aerobic respiration and, as such, adequate molecular mechanisms are more...

Supervisor(s): White, Mark (Dr), Mackay, Joel (Professor)

Develop point-of-care microfluidic technologies for cardiovascular and cerebrovascular diseases

We are developing a clinically useful, rapid and high throughput profiling microdevices for thrombosis and coagulation. It will be extremely useful for patients with diabetes, obesi more...

Supervisor(s): Ju, Lining (Arnold) (Dr)

Develop single-molecule and super-resolution microscopy imaging technologies in the cardiovascular disease

This project will focus on development, improvement, and application of single-molecule tracking and super-resolution imaging, such as TIRF, HiLo, PALM, STORM, Lattice Light-Sheet M more...

Supervisor(s): Ju, Lining (Arnold) (Dr)

Chemical synthesis and phenotypic validation of precision proteolysis targeted chimeras (PROTACs) for cancer and cardiovascular disease

Emerging from the interface between chemistry and biology, chemical biology has led to the establishment of several game-changing drug discovery paradigms. Among these revolutionary more...

Supervisor(s): Liu, Xuyu (Dr), Payne, Richard (Professor)

Modelling plasma synthesis of nanoparticles for non-invasive diagnosis and targeted treatment of disease

This project will develop multiphysics models of a low temperature capacitively coupled plasma reactor to engineer functionalised nanoparticles for biomedical applications.This proj more...

Supervisor(s): Bilek, Marcela (Professor), Baldry, Mark (Dr)

The Physics of Circadian Desynchrony

This project will investigate brain mechanisms and health consequences of circadian misalignment. more...

Supervisor(s): Postnova, Svetlana (Dr)

THE PATHOGENIC AND PROTECTIVE EFFECTS OF MICROGLIA IN CEREBRAL CYTOKINOPATHIES

Microglia are the primary immune cells of the brain and have the potential to both protect and contribute to neurological disease. Explore the molecular mechanisms that microglia us more...

Supervisor(s): Hofer, Markus (Dr)