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Utilising Clinically Relevant Mechanisms to Develop Neuroprotective Strategies in Glaucoma

Neuroprotective strategies for glaucoma therapy have been investigated extensively over the last few years with disappointing clinical trial results. However a significant proportio more...

Supervisor(s): White, Andrew (Dr)

The New Renin-Angiotensin System in the Human Eye

At present, the only treatment for glaucoma is intraocular pressure control. We know some people still get worse despite good pressure control. We have evidence that a system previo more...

Supervisor(s): White, Andrew (Dr)

The Renin-Angiotensin System and its Role in Neuroprotective Strategies in a Glaucoma Model

At present, the only treatment for glaucoma is intraocular pressure control. We know some people still get worse despite good pressure control. We have evidence that a system previo more...

Supervisor(s): White, Andrew (Dr)

Metal Ion Sensors for Medicinal and Environmental Applications

Metal cations like Zn(II), Cu and K(I) play a raft of important signalling roles in our bodies; others such as Hg(II), Cd(II) and Pb(II) are toxic pollutants in the environment. more...

Supervisor(s): Rutledge, Peter (Professor), Canning, John (Honorary Professor)

Cell cycle control of DNA repair in lymphoid cells

PhD opportunity in an NHMRC-funded group to determine how cell cycle determines the fidelity of DNA repair in activated B cells in vivo. more...

Supervisor(s): Jolly, Chris (Dr)

Fluorescent sensors for oxidative stress

Oxidative stress is associated with all diseases of ageing, and there is therefore a need for better tools to identify and quantify the condition. We are developing novel fluorescen more...

Supervisor(s): New, Elizabeth (Associate Professor)

Regulation of host resistance and immune response to human pathogens

The laboratory of Immunology and Host Defense focuses on the immune mechanisms that regulate host resistance to pathogens of global importance. It currently offers multiple projects more...

Supervisor(s): Feng, Carl (Dr)

‘Magic Bullet’ Cancer Drugs and Antibiotics

We are building new kinds of cancer drugs and antibiotics: molecules that change their behaviour in the presence of their biological target, being chemically activated only when the more...

Supervisor(s): Rutledge, Peter (Professor)

Understanding the Switch between Enzyme and Signaling Behaviours in Human Group IIA Secreted Phospholipase A2 by Inhibitory Intervention

The principles of soluble protein structure and ligand docking are applied to structure analysis of membrane bound protein receptors and receptor ligand complexes. more...

Supervisor(s): Church, W Bret (Dr)

LDL-cholesterol controls the role of integrins in cancer cell migration

This project explores the role of LDL-cholesterol in integrin trafficking and signalling, which is relevant for cancer cell migration. more...

Supervisor(s): Grewal , Thomas (Associate Professor)