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Social Policy Research Network

We bring together researchers and practitioners from within the University of Sydney and from non-profit and public sectors. We help coordinate research collaborations, host more...

Supervisor(s): Ravulo, Jioji (Professor), Goodwin, Susan (Professor), Heward-Belle, Susan (Dr), Phillips, Ruth (Associate Professor), Rawsthorne, Margot (Associate Professor), Spencer, Margaret (Dr), Tseris, Emma (Dr)

TARGETING THE BRAIN VASCULATURE AS A TREATMENT FOR CEREBRAL TYPE I INTERFERONOPATHIES

Abnormal blood vessels are feature of cerebral type I interferonopathies. Discover how the endothelial cells that line the brain’s blood vessels contribute to disease in patie more...

Supervisor(s): Hofer, Markus (Dr)

THE PATHOGENIC AND PROTECTIVE EFFECTS OF MICROGLIA IN CEREBRAL CYTOKINOPATHIES

Microglia are the primary immune cells of the brain and have the potential to both protect and contribute to neurological disease. Explore the molecular mechanisms that microglia us more...

Supervisor(s): Hofer, Markus (Dr)

HOW DIFFERENT CELL TYPES OF THE BRAIN CONTRIBUTE TO CEREBRAL CYTOKINOPATHIES

The brain consists of a large number of different cell types, including neurons, astrocytes, oligodendrocytes, microglia and endothelial cells. Discover how these different cell typ more...

Supervisor(s): Hofer, Markus (Dr)

EFFECTS OF TYPE I INTERFERONS IN CHRONIC VIRAL INFECTIONS

When type I interferon signalling is impaired, infection with lymphocytic choriomeningitis virus results in chronic infection and dysfunctional CD8+ T cell function. Investigate how more...

Supervisor(s): Hofer, Markus (Dr)

Precision medicines for GABA-A receptor variants in epilepsy

Developmental and Epileptic Encephalopathies (DEEs) are rare and severe neurological conditions often associated with intellectual disability, developmental delay, autism spectrum d more...

Supervisor(s): Collins, Mary (Professor)

Conserved Regulatory Genes in Neurodevelopment

The present project aims to utilize the promising combination of 3D organoid technology and CRISPR genome editing, which will allow us to examine the roles of several conserved gene more...

Supervisor(s): Neely, Greg (Professor)

Multiscale modelling and simulation of solid-fluid interactions in porous media

The aim of this project is to develop computational tools for modelling the coupled fluid transport-solid deformation behaviour in porous media at micro-, meso- and macro-scales. more...

Supervisor(s): Shen, Luming (Associate Professor)

Controls on the Holocene evolution of the Great Barrier Reef: linking 4D numerical modeling and observational data

This project will investigate the biological and geological processes that control the evolution of coral reef systems (e.g. reef communities, stratigraphic ages and growth rates, r more...

Supervisor(s): Webster, Jody (Professor), Chandra, Rohitash (Dr), Salles, Tristan (Dr)

The anti-apoptotic activity of serum albumin for endothelial cells

Earlier work in my laboratory, established that serum albumin contains a cryptic protein domain that is exposed through transient intra-molecular protein movement, to bind a G-prote more...

Supervisor(s): Zoellner, Hans (Professor)