Facts & figures
SOuRCe research output
- 313 Journal articles published
- 129 Published abstracts
- 322 Presentations
- $16.5 million Grants
- 8 Current PhD students
- 7 current Current Masters students
- 4 Current MD research students
Facts & figures
Research leader: Dr Cherry Koh
In early 2014, an exciting development within academic surgery took place with the creation of the RPA Institute of Academic Surgery (IAS). Established by SLHD, in partnership with the University of Sydney, the IAS aims to promote academic surgery as well as best surgical practice and patient care through research, education and academic career development for surgeons.
To find out more visit the Institute of Academic Surgery website.
Research leader: Associate Professor Matthew Rickard
The Concord colorectal unit is an international centre of excellence in the practice of colorectal surgery, in particular, the training of specialist surgeons in the full range of open, laparoscopic and robotic procedures and in the delivery of best practice care for both patients and their families, especially those suffering from large bowel cancer.
This is empowered by the work of the Concord Colorectal Cancer Registry which has had a leading role in the investigation of the staging and reporting of colorectal cancer and in the development, standardisation, statistical verification and promulgation of the Australian Clinicopathological Staging Classification of CRC, one of six internationally recognised staging classifications endorsed by the NHMRC.
This work together with numerous publications concerning the natural history, the influence of independent prognostic factors and the survival of patients treated for CRC is the basis for the Unit’s regular MDT meetings. They provide the milieu to discuss the complexities of individual patient care and the consideration for adjuvant therapy. In addition, the Registry remains a rich source of information for postgraduate research for both MD students and those advanced trainees wishing to undertake a PhD or higher doctorate studies.
The colorectal unit also undertakes extensive research in benign colorectal diseases, including inflammatory bowel disease and proctology.
Research leader: Associate Professor Sarah Aitken
Our research focuses upon innovative vascular technology, vascular surgical outcomes (especially in older patients) and surgical education. We have current projects on endoanchors for EVAR, measuring vascular outcomes with data-linkage, patient-centred outcomes and experiences in vascular disease. Our unit works closely in collaboration with the Geriatrics unit at Concord Hospital, the Centre for Education and Research in Ageing and the Ageing and Alzheimers Association. Researchers within out unit have received grant funding from the Vascular Foundation, RACS college, Sydney Medical Foundation and the University of Sydney.
Research leader: Professor Guy Eslick
The Department of Surgery at Nepean Hospital conducts research in general surgery, the acute surgical unit, upper GI surgery, breast/endocrine surgery, orthopedic surgery, surgical education, surgical oncology, colorectal surgery, hepatobiliary surgery, and urological surgery.
The Whiteley-Martin Research Centre was opened in 2010 to conduct evidence-based surgical research into oesophageal and gastric cancer. Professor Michael Cox and Professor Guy Eslick are Co-Directors of The Whiteley-Martin Research Centre.
Research interests include:
There is a strong focus in fundamental and translational research. Telehealth, surgical safety and quality are recent additions, with Nepean Hospital being one of the four pilot sites for the introduction of the American College of Surgeons (ACS) National Safety and Quality Improvement program (NSQIP).
Research leader: Dr Jonathon Parkinson
Research is undertaken across a broad range of surgical specialties at Royal North Shore Hospital. Collectively, the surgeons of RNSH have formed the Surgical Education, Research and Training (SERT) Institute to formalise collaboration, pool resources and promote surgical academia on the RNSH campus. The key objectives of the SERT Institute are to:
Each of the surgical departments have provided an Academic Lead and through these leads the individual surgical departments are provided with resources to facilitate their individual research.
Royal North Shore Hospital has the luxury of being co-located with the Kolling Institute of Medical Research. The Kolling Institute was established in 1920 making it the oldest medical research institute in NSW. There is a strong focus on collaborative, translational research within the Kolling, and surgeons of various specialties contribute to a number of the groups within the Kolling Institute including the Bill Walsh Translational Cancer Research Laboratory, the Raymond Purves Bone and Joint Research Laboratory, the Cancer Genetics Laboratory and others.
Other research groups on the RNSH campus thatfocus on surgical research include:
Research leader: Associate Professor Manish Patel
Research at the Westmead Department of Surgery ranges from laboratory based basic research, through to translational bench to bed-side research, clinical outcomes research and clinical trials. Research projects are available that would suit all students ranging from MD projects to Masters and PhDs.
The department has also established a dedicated surgical trials centre to enable surgeons to deliver clinical studies to assess new surgical techniques and develop breakthroughs in treatment that will help deliver new and better care to hundreds of patients.
This research centre was established in 2010 with a grant from the NSW Cancer Institute. It aims to complete high quality clinical research to improve oncological and quality of life for patients with prostate, bladder and kidney cancer. This is achieved by completing research on a number of levels:
Collaborations with the NSW Cancer Council have given access to population datasets (APDC/Cancer registry) and large cohort studies (45 and up) which allows investigation of patterns of care and cancer outcomes for patients in NSW.
Research from datasets collected from treated patients allows the investigation of oncological and quality of life outcomes from patients treated at Westmead. This then leads to quality improvement and investigational trials leading to improvement.
The department of Urology places a strong emphasis on clinical trials. We currently have 7 surgical clinical trials open for urological cancers.
Current major research projects:
Research leader: Professor Henry Pleass
Westmead hospital is home to the Federally funded National Pancreas Transplant Unit, one of only two such units in Australia. Much of our clinical research has focussed on pancreas graft and patient outcomes. We have also supervised two PhD students over the last three years, one full time and one part time, the former submitting their thesis on improving organ transplant outcomes through amelioration of the ischaemia reperfusion injury.
Current clinical projects include:
Current biomedical engineering collaboration:
Research leader: Dr James Toh
The academic colorectal unit at Westmead Hospital has numerous multi-centre collaborations with research groups in Australia, New Zealand and internationally, including with Korea University Anam Hospital.
Currently, our focus is on translational research into inflammatory bowel disease, colorectal cancer and diverticulitis, as well as clinical studies into the role of enhanced recovery after surgery (ERAS), bowel preparation and oral antibiotics and robotic rectal cancer surgery. The unit is part of the mucosal immunology group exploring the role of innate lymphoid cells in the aetiology of Crohn’s disease.
We recently published the largest cohort of inflammatory bowel disease patients in Australia with a focus on surgical management. We are also looking into the impact of microsatellite instability and Lynch syndrome in colorectal cancer, the immune landscape and role of checkpoint inhibitors in colon and rectal cancer.
As part of a multicentre trial, we are involved in the CAPP3 study on the role of aspirin in colorectal cancer. Our unit was recently awarded a CINSW grant to look at variations in colorectal cancer surgery. Westmead hospital is also involved in the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) looking at improving the performance of surgical units based on a nationwide analysis. Our unit published the first NSQIP study outside of America on the role of mechanical bowel preparation and oral antibiotics in reducing surgical site infection, which we have now expanded into a quality improvement project in our district. Our unit is currently working on developing a risk calculator for morbidity and mortality for patients undergoing major colorectal procedures.
Research leader: Dr Muzib Abdul-Razak
Surgical oncology and head and neck have a collaborative approach to research with colleagues in cancer services, particularly radiation oncology. The areas of interest are Merkel Cell carcinoma, cutaneous squamous cell carcinoma and upper aerodigestive tract cancers particularly oral cancers. One of our surgeons is undertaking a PhD related to sentinel node biopsy of oral cancers.
We also work collaboratively with medical oncology at Westmead and Radiation Oncology at Prince of Wales sarcoma unit in projects relating to melanoma and sarcoma management.
Established in 2002, the Surgical Outcomes Research Centre (SOuRCe) is a multidisciplinary, academic research unit of the University of Sydney and the Sydney Local Health District. Our location at Royal Prince Alfred Hospital ideally places us to make collaborative and multi-disciplinary research a reality.
SOuRCe joined the RPA Institute of Academic Surgery (IAS) when it was established in 2014 in partnership with the SLHD and the University of Sydney. Research conducted within the centre addresses the full spectrum of evidence-based surgical practice:
Over the last few years, SOuRCe has developed three major flagship programs in research.
To find out more visit: source.org.au
Giving today. Changing tomorrow.
When an operation for brain cancer left a nine-year-old boy's face paralysed, a University surgeon and an anonymous donor stepped in to help.