Skip to main content
News_

Parental diet affects offspring immunity: meta-analysis

27 November 2017
Research across the animal kingdom has implications for humans

A multidisciplinary wide-ranging study has found a close relationship exists between parents' diets and the immunity of offspring, with implications for wildlife conservation and agriculture as well as human health.

The impacts of a parent’s diet can extend beyond birth to affect the health of the child.

Photo credit: Inferis [CC BY-SA 2.0] via Wikimedia Commons

A review of studies about parents’ diet and the immunity of animal offspring has found a close relationship exists, with implications for wildlife conservation and livestock rearing as well as human health.

The meta-analysis – which shows the intergenerational immunological response continues even when the offspring are raised on a normal diet – looked at hundreds of results published in 38 published papers across a range of animal species, including rodents, primates and birds.

The findings are published today in the high-impact journal Biological Reviews.

The paper is a cross-disciplinary effort spearheaded at the University of Sydney, by lead author Dr Catherine Grueber who undertook the research at the Sydney School of Veterinary Science  and including co-author Professor Stephen Simpson from the School of Life and Environmental Sciences, who directs the lifestyle diseases-focused Charles Perkins Centre.

Dr Grueber said the study showed the close relationship between diet and immunity exists across the animal kingdom and that poor nutrition can negatively affect many traits, including disease resistance.

“Our meta-analysis suggests that the effects of a parental diet on immunity can be inherited and that this ‘signal’ is maintained in offspring in the short term, even if offspring are on the normal diet for their species,” Dr Grueber said.

“Researchers are now following a range of leads to discover exactly what that ‘signal’ is, what the long-term consequences are and whether the effects can be reversed if offspring continue to eat a healthy diet as they grow.”

Professor Simpson said the results could be relevant to humans and add to the body of evidence in support of healthy diets while pregnant.

“We already know that parents need to be mindful of maintaining a healthy diet not only during pregnancy but also before they conceive,” Professor Simpson said.

“This study demonstrates that the impacts of a parent’s diet can extend beyond birth to affect the health of the child.”

The authors of the paper are: Catherine Grueber, University of Sydney’s School of Life and Environmental Sciences and San Diego Zoo Global; Lindsey Gray and Stephen Simpson, University of Sydney’s Charles Perkins Centre and School of Life and Environmental Sciences; Alistair Senior, University of Sydney’s Charles Perkins Centre and School of Mathematics and Statistics; and Katrina Morris, The Roslin Institute, University of Edinburgh.

Vivienne Reiner

Media and PR Adviser (Science, Veterinary Science, Agriculture)
Address
  • Room 192, Level 1 Carslaw F07

Related articles

02 July 2020

Has COVID-19 boosted interest in physical activity?

Have you searched online for 'home-based exercise' or 'high-intensity workout' recently? Turns out you're not the only one.
02 July 2020

‘Healthy’ snack foods big on marketing, small on nutrition

Confused by excessive buzzwords on your granola bar packaging? Nutrition researchers at the University of Sydney have found that is likely a deliberate ploy.
30 June 2020

Native Grains: Narrabri researchers meet with Aboriginal community

Indigenous knowledge and agricultural science are uniting to help support a renaissance in Aboriginal agriculture in western NSW. The winners will include farmers looking for additional income streams.
30 June 2020

Dogs, thunderstorms and fireworks: the fear is real

Dogs with noise phobias show symptoms including panting, pacing and hiding. They are often so frightened they try and escape and can sustain injuries in the process. Because of this, fearful dogs can be a danger to themselves.
26 June 2020

Did COVID-19 models get it wrong? Professor Sally Cripps explains

Renowned University of Sydney statistician, Professor Sally Cripps, examines the efficacy of COVID-19 modelling as part of an online analysis with colleagues from Stanford University and North-Western University.