Skip to main content
News_

Parental diet affects offspring immunity: meta-analysis

27 November 2017

A multidisciplinary wide-ranging study has found a close relationship exists between parents' diets and the immunity of offspring, with implications for wildlife conservation and agriculture as well as human health.

The impacts of a parent’s diet can extend beyond birth to affect the health of the child.

Photo credit: Inferis [CC BY-SA 2.0] via Wikimedia Commons

A review of studies about parents’ diet and the immunity of animal offspring has found a close relationship exists, with implications for wildlife conservation and livestock rearing as well as human health.

The meta-analysis – which shows the intergenerational immunological response continues even when the offspring are raised on a normal diet – looked at hundreds of results published in 38 published papers across a range of animal species, including rodents, primates and birds.

The findings are published today in the high-impact journal Biological Reviews.

The paper is a cross-disciplinary effort spearheaded at the University of Sydney, by lead author Dr Catherine Grueber who undertook the research at the Sydney School of Veterinary Science  and including co-author Professor Stephen Simpson from the School of Life and Environmental Sciences, who directs the lifestyle diseases-focused Charles Perkins Centre.

Dr Grueber said the study showed the close relationship between diet and immunity exists across the animal kingdom and that poor nutrition can negatively affect many traits, including disease resistance.

“Our meta-analysis suggests that the effects of a parental diet on immunity can be inherited and that this ‘signal’ is maintained in offspring in the short term, even if offspring are on the normal diet for their species,” Dr Grueber said.

“Researchers are now following a range of leads to discover exactly what that ‘signal’ is, what the long-term consequences are and whether the effects can be reversed if offspring continue to eat a healthy diet as they grow.”

Professor Simpson said the results could be relevant to humans and add to the body of evidence in support of healthy diets while pregnant.

“We already know that parents need to be mindful of maintaining a healthy diet not only during pregnancy but also before they conceive,” Professor Simpson said.

“This study demonstrates that the impacts of a parent’s diet can extend beyond birth to affect the health of the child.”

The authors of the paper are: Catherine Grueber, University of Sydney’s School of Life and Environmental Sciences and San Diego Zoo Global; Lindsey Gray and Stephen Simpson, University of Sydney’s Charles Perkins Centre and School of Life and Environmental Sciences; Alistair Senior, University of Sydney’s Charles Perkins Centre and School of Mathematics and Statistics; and Katrina Morris, The Roslin Institute, University of Edinburgh.

Vivienne Reiner

Media and Public Relations Adviser | Health
Address
  • A15 - Pharmacy & G02 - Jane Foss Russell Building Pharmacy A15

Related articles

22 July 2021

No progress: Physical inactivity remains a global pandemic

Experts are calling for urgent action to improve physical activity worldwide, with research showing no progress in nearly a decade and that the Olympics are a missed opportunity to change health at the population level.
20 July 2021

Touchscreen alternative allays fear of world indium shortage

Indium is used to manufacture touchscreens and other smart devices, but there is no guaranteed, long-term supply of this scarce substance. A new plasma technology may be the answer, writes Dr Behnam Akhavan.
20 July 2021

Plasma tech could replace one of world's rarest materials

New plasma coating technology could see the phase-out of rare earth metal indium that is used in smartphone glass and dimmable windows, which is predicted to run out in 10 years.
20 July 2021

How the science of wellbeing can help build resilience

From teddy bears in windows to panic buying, the COVID-19 pandemic has shown how crises can elicit different human behaviours. A University of Sydney expert is calling for a shift in thinking from 'me' to 'we' to bolster communities through the pandemic.
19 July 2021

Review of Australian COVID-19 research finds lack of collaboration and crucial gaps

Researchers are calling for improved national coordination of Australian COVID-19 trials, after analysis finds lack of data sharing and collaboration resulting in crucial research gaps.