Staff using our mass spectrometry facilities

Sydney Mass Spectrometry

"-omics" specialists for the life sciences
Sydney Mass Spectrometry provides state–of-the-art tools and expertise for proteomics, metabolomics and mass spectrometry imaging for the life and biomedical science communities.

Sydney Mass Spectrometry provides access to cutting-edge instrumentation and expert assistance for proteomics, glycomics, metabolomics, lipidomics, and mass spectrometry imaging.

Our facilities feature a diverse portfolio of 20 mass spectrometers, with extensive data processing and analysis packages, and are located on two sites: the Charles Perkins Centre at the University of Sydney and the Kolling Institute at the Royal North Shore Hospital. 

Our specialist technical staff have over 50 years’ combined experience and are on hand to provide high-level training, project development, and contract research services.

We welcome enquiries regarding our range of research services available on a contractual basis. Examples of our services include:

  • Whole mass analysis – checks the quality and purity of synthetic peptides or purified proteins. It can be successfully applied to proteins up 175 kDa in size
  • Peptide mass fingerprinting (PMF) – commonly used to identify proteins from 1D or 2D gels. It can be used to determine approximate sites of cleavage in the event of partial proteolysis of purified proteins, or the incorporation of labels such as deuterium, N15 or selenomethionine
  • One dimensional liquid chromatography coupled to tandem mass spectrometry (1D LC-MS) can be used to identify proteins. Unlike PMF, 1D LC-MS can identify 10-100’s of proteins in semi-complex mixtures. Typical applications include identifying binding partners in pull-down assays
  • Quantitative shotgun proteomics – for a comprehensive analysis of complex protein mixtures which are first digested with a protease and then the peptides are separated by multidimensional liquid chromatography. It typically identifies and quantifies thousands of proteins.

Sydney Mass Spectrometry Symposium 2024

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Research Case Studies

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Sydney Mass Spectrometry

  • Sydney Mass Spectrometry has locations across multiple sites including the Charles Perkins Centre on the University of Sydney Camperdown campus, and the Kolling Institute on the Royal North Shore Hospital grounds. Our headquarters are in the Charles Perkins Centre.
Delivery address
Sydney Mass Spectrometry via The Hub Loading Dock, Charles Perkins Centre (D17) Orphans School Creek Lane, Camperdown University of Sydney, NSW 2006 Dock receiving time: 08:00 – 16:00, Mon - Fri.

Locations include

Charles Perkins Centre

Kolling Institute