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Unit of study_

BMET9962: Introduction to Mechanobiology

This course introduces you to Mechanobiology an emerging field of science that integrates biology and engineering and is now considered to have significant influence on the development of technologies for regenerative medicine. It is well known that tissues and cells are sensitive to their mechanical environment and changes to this environment can affect the physiological and pathophysiological processes. Understanding the mechanisms by which biological cells sense and respond to mechanical signals can lead to the development of novel treatments and therapies for a variety of diseases. The student will gain fundamental insights to the topics related to intracellular network, mechanotransduction, nanomechanical tools in mechanobiology, ECM mechanics and artificial matrix platforms and application of mechanobiology in various pathophysiological processes. The course has a strong practical component to have hands on experience in developing artificial matrix with various mechanical properties, stem cell culture, cell differentiation, staining and imaging.

Code BMET9962
Academic unit Biomedical Engineering
Credit points 6
AMME5962 or BMET5962 or BMET3962
Assumed knowledge:
6 credit points of 1000-level biology, 6 credit points of 1000-level chemistry and 6 credit points of 2000-level physiology or equivalent

At the completion of this unit, you should be able to:

  • LO1. Demonstrate effective oral communications skills, understand research questions, and critically analyze and interpret data
  • LO2. Obtain information using appropriate search strategies to gain in-depth knowledge and current advances in mechanobiology through peer-reviewed research resources
  • LO3. Understand the basic principles of mechanobiology and its importance in the field of biomedical engineering and regenerative medicine.
  • LO4. Apply and integrate engineering principles to biological processes. Utilizing biomedical devices to understand the principles of mechanobiology.
  • LO5. Understand the use of engineering technologies and analytical tools in the field of mechanobiology, applications and design of biomaterial platforms in the field of mechanobiology
  • LO6. Demonstrate the procedure for working safely, correctly, and effectively in a molecular biology laboratory. Learn and demonstrate a range of practical techniques in molecular biology, stem cell culture and differentiation, develop biomaterial platforms to understand the principles of mechanobiology. Demonstrate a collaborative experimental work, effective data acquisition, analysis, imaging, data recording.
  • LO7. Demonstrate comprehensive and integrated report writing related to the activities in the lab with critical analysis of the data obatained.

Unit outlines

Unit outlines will be available 1 week before the first day of teaching for the relevant session.