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Unit of study_

BSTA5013: Statistical Genomics (SGX)

2024 unit information

Statistical genomics is the application of statistical methods to understand genomes, their structure, function and history, in many different scientific contexts, including understanding biological mechanisms in health and disease. Statistical genomics is characterised by large datasets, high-dimensional regression models, stochastic processes, and computationally-intensive statistical methods. The aim of this unit is to learn about relevant biology and terminology, to understand the most important mathematical models and inference methods in statistical genetics, to be able to test for association between genetic variants and outcomes of interest, and to use genome-wide statistical models to help understand the genetic mechanisms underlying a trait and to predict outcomes. The statistical package R will be used to perform regression-based analyses of genetic data.

Unit details and rules

Managing faculty or University school:

Public Health

Code BSTA5013
Academic unit Public Health
Credit points 6
BSTA5004 and (BSTA5210 or BSTA5211 or BSTA5007)

At the completion of this unit, you should be able to:

  • LO1. Describe core mechanisms of genetics, including mutation, recombination and selection
  • LO2. Use the Wright-Fisher and coalescent models of population genetics for simulation and inference
  • LO3. Perform sequence analysis using hidden Markov models
  • LO4. Describe the key data, models and inference goals of phylogenetics
  • LO5. Access genomic data from public databases
  • LO6. Perform a genetic association analysis, including the assessment of possible confounding
  • LO7. Explain the concept of heritability and its estimation
  • LO8. Use genome-wide SNP data to develop prediction models
  • LO9. Explain key features of data and statistical models used in the fields of transcriptomics, epigenetics, and bacterial genomics
  • LO10. Effectively communicate results of statistical analyses in genomics and related areas

Unit availability

This section lists the session, attendance modes and locations the unit is available in. There is a unit outline for each of the unit availabilities, which gives you information about the unit including assessment details and a schedule of weekly activities.

The outline is published 2 weeks before the first day of teaching. You can look at previous outlines for a guide to the details of a unit.

Session MoA ?  Location Outline ? 
Semester 2 2023
Online Camperdown/Darlington, Sydney
Session MoA ?  Location Outline ? 
Semester 2 2024
Online Camperdown/Darlington, Sydney
Outline unavailable
Session MoA ?  Location Outline ? 
Semester 2 Early 2020
Online Camperdown/Darlington, Sydney
Outline unavailable
Semester 2 2021
Online Camperdown/Darlington, Sydney

Modes of attendance (MoA)

This refers to the Mode of attendance (MoA) for the unit as it appears when you’re selecting your units in Sydney Student. Find more information about modes of attendance on our website.