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Unit of study_

CHEM3118: Synthetic Chemistry

2025 unit information

Over 144 million chemical substances are known, many of which possess a complex arrangement of atoms and bonds that lead to unique and intricate 3-dimensional structures. Chemical structure is directly related to the function of molecules. While the structures of many known compounds have been built using the limited set of reactions that are employed by Nature, not all chemical structures can be accessed this way. Synthetic chemists have developed a multitude of reactions and strategies to build molecules that can't be accessed using Nature's toolkit. These can be applied to the creation of manufactured chemicals that improve our everyday lives, including medicines, fabrics, coatings, and in food production. In this unit you will learn fundamental strategies and reactions that can be used to create new molecular structures. You will investigate strategies that allow the synthesis of specific isomers to interact with the chiral world we live in, including molecules that cure disease. You will learn modern synthetic reaction methods that mitigate the environmental impact of chemical synthesis. By doing this unit you will develop an understanding of how chemical bonds can be broken and formed in a directed manner to build new molecular architectures with specific properties and 3-dimensional shapes.

Unit details and rules

Managing faculty or University school:

Science

Study level Undergraduate
Academic unit Chemistry Academic Operations
Credit points 6
Prerequisites:
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[(CHEM2401 or CHEM2911 or CHEM2915) and (CHEM2402 or CHEM2524 or CHEM2912 or CHEM2916 or CHEM2924)] or (CHEM2521 or CHEM2921 or CHEM2991)
Corequisites:
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None
Prohibitions:
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CHEM3115 or CHEM3915 or CHEM3918
Assumed knowledge:
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None

At the completion of this unit, you should be able to:

  • LO1. ​Explain the importance of selectivity in synthesis, including chemoselectivity, regiochemoselectivity, diastereoselectivity, and enantioselectivity.
  • LO2. Apply your knowledge of chemical reactivity for the selection of appropriate protecting groups.
  • LO3. Analyse molecules using retrosynthetic strategies​
  • LO4. Evaluate observed selectivity across a range of chemical transformations and invent synthetic pathways that could be used to synthesize target molecules in a highly selective fashion.​
  • LO5. Carry out experimental work safely and competently in a chemical laboratory​
  • LO6. Develop skills to work collaboratively in responsible data collection, analysis and communication and advanced chemical enquiry.​
  • LO7. ​Evaluate and interpret scientific information and experimental data and judge their reliability and significance​
  • LO8. Communicate scientific information and laboratory findings appropriately both orally and through written work​

Unit availability

This section lists the session, attendance modes and locations the unit is available in. There is a unit outline for each of the unit availabilities, which gives you information about the unit including assessment details and a schedule of weekly activities.

The outline is published 2 weeks before the first day of teaching. You can look at previous outlines for a guide to the details of a unit.

Session MoA ?  Location Outline ? 
Semester 1 2024
Normal day Camperdown/Darlington, Sydney
Session MoA ?  Location Outline ? 
Semester 1 2025
Normal day Camperdown/Darlington, Sydney
Outline unavailable
Session MoA ?  Location Outline ? 
Semester 1 2021
Normal day Camperdown/Darlington, Sydney
Semester 1 2021
Normal day Remote
Semester 1 2022
Normal day Camperdown/Darlington, Sydney
Semester 1 2022
Normal day Remote
Semester 1 2023
Normal day Camperdown/Darlington, Sydney
Semester 1 2023
Normal day Remote

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Modes of attendance (MoA)

This refers to the Mode of attendance (MoA) for the unit as it appears when you’re selecting your units in Sydney Student. Find more information about modes of attendance on our website.